Effect of Chrysanthemum Flower Oil and Its Dose-dependency on Hyperuricemia

Not Applicable

Completed

• Conditions: Hyperuricemia
• Interventions: Dietary Supplement: 200 mg of chrysanthemum flower oil; Dietary Supplement: 400 mg of chrysanthemum flower oil; Dietary Supplement: 300 mg of chrysanthemum flower oil

• Registration Number: NCT02213562
• Lead Sponsor: Hiroshima University

Brief Summary

The aim of this study is to investigate the efficacy and dose-dependency of chrysanthemum flower oil in suppressing serum uric acid.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-08-08
• Study First Submitted QC: 2014-08-08
• Study First Posted: 2014-08-11
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-15
• Last Update Posted: 2016-08-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 21

Inclusion Criteria

• Serum uric acid 6.8-8.9 mg/dL

Exclusion Criteria

• Taking anti-hyperuricemic drugs
• History of gouty attack
• Taking drugs or functional food that may affect serum uric acid level
• Hypertention, hyperlipidemia, or diabetes millitus
• Participation in any clinical trial within 90 days of the commencement of the trial
• Renal or hepatic dysfunction
• Heart disease
• History of severe disease and/or major surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
200 mg CFO	200 mg of chrysanthemum flower oil	200 mg of chrysanthemum flower oil
400 mg CFO	400 mg of chrysanthemum flower oil	400 mg of chrysanthemum flower oil
300 mg CFO	300 mg of chrysanthemum flower oil	300 mg of chrysanthemum flower oil

Primary Outcome Measures

Name	Time	Method
Change in serum uric acid from baseline	Every 4 weeks (Overall 8 weeks)
Change in uric acid clearance from baseline	Every 4 weeks (Overall 8 weeks)

Trial Locations

Locations (1)

Hiroshima University; 🇯🇵 Hiroshima, Japan