Comparison of two different techniques(insulin bolus vs glucose insulin infusion) to control blood glucose levels during surgery

Not yet recruiting

Conditions: Type 2 diabetes mellitusPreoperative fasting blood glucose value more than 150mg/dlSurgery duration of â‰¥ 1hour

Registration Number: CTRI/2017/12/011037

Lead Sponsor: Dr Arun P

Brief Summary: Patients with diabetes undergo surgical procedures at a higher rate than nondiabetic people. Major surgical operations require a period of fasting during which oral antidiabetic medications cannot be used and the stress of surgery results in metabolic perturbations that alter glucose homeostasis. Electrolytes imbalance due altered glucose levels (principally potassium, but also magnesium) may increase the risk for arrhythmias. It is therefore imperative that careful attention should be paid to the metabolic status of diabetic patients undergoing surgical procedures. Intraoperative management of blood glucose in diabetes mellitus patients has focused on avoidance of profound hypoglycemia or hyperglycemia. There are many regimens that are described for perioperative blood glucose control each having its own advantages and disadvantages. We plan to compare the intraoperative glycemic levels between insulin bolus regimen and glucose insulin infusion regimen.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 120

Inclusion Criteria

Type 2 diabetes mellitus Preoperative fasting blood glucose value >150mg/dl Surgery duration of â‰¥ 1hour.

Exclusion Criteria

Patients with a history of cardiac, respiratory, renal or hepatic failure Patients undergoing cardiac surgery Patients having active infection Patients on steroid therapy Pregnant female Patients with serum potassium below the reference range (<3.5 mmol/L).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of patients in the target glucose levels between 100 mg/dL and 180 mg/dL	Every hour of surgery

Secondary Outcome Measures

Name	Time	Method
Serum potassium levels	1 hour postoperatively

Trial Locations

Locations (1): Kasturba Hospital
🇮🇳
Udupi, KARNATAKA, India
Kasturba Hospital
🇮🇳Udupi, KARNATAKA, India
Dr Arun P
Principal investigator
9600129686
p.arun1991@gmail.com