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RNA as Prognostic Biomarkers in Patients With Acute Coronary Syndrome

Recruiting

Conditions: Coronary Syndrome

First Posted Date: 2023-09-28

Last Posted Date: 2023-10-06

Lead Sponsor: IRCCS Policlinico S. Donato

Target Recruit Count: 70

Registration Number: NCT06058182

Locations: 🇮🇹
IRCCS Policlinico S. Donato, Milan, Italy, Milano, Milan, Italy

CRISPR/cas13-medIated RNA TarGeting THerapy for the Treatment of Neovascular Age-related Macular Degeneration Investigator-initiated Trial (SIGHT-I)

Early Phase 1

Recruiting

Conditions: Neovascular Age-related Macular Degeneration(nAMD)

Interventions: Genetic: HG202

First Posted Date: 2023-09-11

Last Posted Date: 2025-03-17

Lead Sponsor: HuidaGene Therapeutics Co., Ltd.

Target Recruit Count: 12

Registration Number: NCT06031727

Locations: 🇨🇳
Eye & ENT Hospital of Fudan University, Shanghai, Shanghai, China
🇨🇳
Tianjin Medical University Eye Hospital, Tianjin, Tianjing, China

SARS-COV-2 Detection From Used Surgical Mask

Not Applicable

Completed

Conditions: SARS-CoV-2 Virus

Interventions: Diagnostic Test: SARS-CoV-2 RNA detection

First Posted Date: 2023-09-07

Last Posted Date: 2024-11-15

Lead Sponsor: Bangkok Metropolitan Administration Medical College and Vajira Hospital

Target Recruit Count: 269

Registration Number: NCT06027398

Locations: 🇹🇭
2 Division of Nephrology,Department of Medicine Pramongkutklao Hospital and College of Medicine,Thailand, Bangkok, Thailand

a Study in Subjects With Otoferlin Mutation-related Hearing Loss Using RNA Base-eDiting Therapy(SOUND)

Early Phase 1

Withdrawn

Conditions: Congenital Hearing Loss

Interventions: Genetic: HG205

First Posted Date: 2023-09-06

Last Posted Date: 2025-04-10

Lead Sponsor: HuidaGene Therapeutics Co., Ltd.

Target Recruit Count: 6

Registration Number: NCT06025032

Locations: 🇨🇳
Eye & ENT Hospital of Fudan University, Shanghai, China
🇨🇳
Eye & ENT Hospital of Fudan University, Shanghai, China

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Not Applicable

Recruiting

Conditions: Atypical Hemolytic Uremic Syndrome
Autosomal Dominant Polycystic Kidney
Membranoproliferative Glomerulonephritis
Healthy

Interventions: Procedure: Skin biopsy

First Posted Date: 2023-08-18

Last Posted Date: 2025-05-09

Lead Sponsor: Mario Negri Institute for Pharmacological Research

Target Recruit Count: 105

Registration Number: NCT05996731

Locations: 🇮🇹
Centro di Ricerche Cliniche per le Malattie Rare "Aldo e Cele Daccò", Ranica, BG, Italy

A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals

Phase 2

Completed

Conditions: SARS-CoV-2 Infection
COVID-19

Interventions: Biological: BNT162b2 (Omi XBB.1.5)
Biological: BNT162b2 (Omi JN.1)
Biological: BNT162b2 (Omi KP.2)

First Posted Date: 2023-08-18

Last Posted Date: 2025-03-28

Lead Sponsor: BioNTech SE

Target Recruit Count: 1051

Registration Number: NCT05997290

Locations: 🇺🇸
North Alabama Research Center, Athens, Alabama, United States
🇺🇸
Medical Affiliated Research Center, Huntsville, Alabama, United States
🇺🇸
Alliance for Multispecialty Research, LLC, Norfolk, Virginia, United States

and more 29 locations

The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis

Active, not recruiting

Conditions: Epithelial Mesenchymal Transition
Long Noncoding RNA
Periodontal Disease, AVDC Stage 3and 4

Interventions: Other: periodontitis challenge

First Posted Date: 2023-08-16

Last Posted Date: 2023-12-12

Lead Sponsor: Ali A Abdulkareem

Target Recruit Count: 48

Registration Number: NCT05995067

Locations: 🇮🇶
saif mohammed T AL Mufti, Baghdad, Iraq

Dynamic Changes of Serum HBV RNA in Chronic Hepatitis B Patients

Not yet recruiting

Conditions: Chronic Hepatitis B Patients

First Posted Date: 2023-08-14

Last Posted Date: 2023-08-16

Lead Sponsor: Beijing Friendship Hospital

Target Recruit Count: 100

Registration Number: NCT05991531

Locations: 🇨🇳
Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing, China

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

Recruiting

Conditions: Lung Cancer

First Posted Date: 2023-08-14

Last Posted Date: 2024-01-16

Lead Sponsor: Hummingbird Diagnostics

Target Recruit Count: 2000

Registration Number: NCT05987189

Locations: 🇺🇸
Northside Hospital, Atlanta, Georgia, United States
🇺🇸
Mass General Brigham, Boston, Massachusetts, United States
🇺🇸
Jacobi Medical Center, Bronx, New York, United States

and more 5 locations

ALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis Approach

Recruiting

Conditions: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis, Sporadic

Interventions: Diagnostic Test: Saliva sample

First Posted Date: 2023-07-03

Last Posted Date: 2024-04-10

Lead Sponsor: ZIWIG

Target Recruit Count: 600

Registration Number: NCT05928416

Locations: 🇫🇷
CHU Strasbourg, Strasbourg, Alsace, France
🇫🇷
CHU Nantes, Saint-Herblain, Loire-Atlantique, France
🇫🇷
CHU Caen, Caen, France

and more 16 locations