Assistance Publique des Hôpitaux de Paris SA

🇫🇷France

Country: 🇫🇷France

Ownership: Private

Established: 1849-01-01

Employees: 10K

Market Cap: -

Website: http://www.aphp.fr

Clinical Trials

Immunogenicity and Reactogenicity Following a Booster Dose of COVID-19 mRNA Vaccine (Pfizer-BioNtech) and Two Adjuvanted Sub-unit Vaccines (SP/GSK) Administered in Adults Who Received 2 Doses of Pfizer-BioNTech mRNA Vaccine as a Primary Vaccination

Phase 3

Conditions: Vaccine Reaction
COVID-19

Interventions: Biological: BNT162b2
Biological: CoV2 preS dTM adjuvanted vaccine (D614), Sanofi/GSK
Biological: CoV2 preS dTM adjuvanted vaccine (B.1.351), Sanofi/GSK

First Posted Date: 2021-11-17

Last Posted Date: 2022-07-11

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 247

Registration Number: NCT05124171

Locations: 🇫🇷
GH Broca-Cochin-Hôtel-Dieu CIC 1417 Cochin-Pasteur, Paris, France

Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease

Completed

Conditions: Marfan Syndrome

Interventions: Other: Questionnaire

First Posted Date: 2021-11-17

Last Posted Date: 2023-01-03

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 90

Registration Number: NCT05123339

Locations: 🇫🇷
CNMR Bichat, Paris, IDF, France

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus

Phase 3

Recruiting

Conditions: Catheter Bacteremia
Staphylococcus Aureus Infection

Interventions: Drug: Standard antibiotic therapy
Drug: Dalbavancin administration

First Posted Date: 2021-11-11

Last Posted Date: 2025-04-06

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 406

Registration Number: NCT05117398

Locations: 🇫🇷
Infectious Diseases Department, Raymond-Poincaré Hospital - APHP, Garches, France
🇫🇷
Infectious Diseases Department, CH PERIGUEUX, Périgueux, France

Isatuximab in Type I Cryoglobulinemia

Phase 2

Conditions: Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance
Cryoglobulinemic Vasculitis

Interventions: Drug: Isatuximab Injection

First Posted Date: 2021-11-09

Last Posted Date: 2021-11-09

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 21

Registration Number: NCT05114109

Effect of Intravenous Iron Supplementation on Celiac Disease Remission (IRONCEL)

Phase 4

Not yet recruiting

Conditions: Celiac Disease

Interventions: Drug: Ferinject
Drug: oral iron

First Posted Date: 2021-11-09

Last Posted Date: 2022-01-19

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 204

Registration Number: NCT05114278

Locations: 🇫🇷
Hôpital Cochin, Paris, France

New Clinical End-points in Patients With Primary Sjögren's Syndrome

Phase 2

Recruiting

Conditions: Primary Sjögren's Syndrome (pSS)

Interventions: Drug: Hydroxychloroquine 400mg/d
Drug: Placebo of Hydroxychloroquine 400mg/d
Drug: Leflunomide 20mg/d
Drug: Placebo of Leflunomide 20mg/d
Drug: Mycophenolate mofetil 2000mg/d
Drug: Placebo of Mycophenolate mofetil 2000mg/d

First Posted Date: 2021-11-09

Last Posted Date: 2024-11-01

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 300

Registration Number: NCT05113004

Locations: 🇫🇷
Eric Hachulla, Lille, France
🇫🇷
Raphaele Seror, Le Kremlin-Bicêtre, Ile De France, France
🇫🇷
Jacques Morel, Montpellier, France

and more 4 locations

Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative

Phase 2

Active, not recruiting

Conditions: Hepatocellular Carcinoma

Interventions: Drug: Lenvatinib Pill

First Posted Date: 2021-11-09

Last Posted Date: 2024-08-01

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 32

Registration Number: NCT05113186

Locations: 🇫🇷
NAHON, Bobigny, France

Alteration of Dermal Elastic Fibers During Calcifying Dermatosis: Structural Study Using Multiphoton Microscopy

Conditions: Dermatosis

First Posted Date: 2021-11-09

Last Posted Date: 2021-11-09

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 30

Registration Number: NCT05112744

Locations: 🇫🇷
Service de gériatrie plaies et cicatrisation, Paris, France

LIPId Profile Changes in Inflammatory Conditions Induced by SARS-CORoronavirus-2

Conditions: SARS-CoV2 Infection

Interventions: Biological: Deep nasopharyngeal swab
Biological: Blood sample at D1, D3 and D7

First Posted Date: 2021-11-09

Last Posted Date: 2021-11-09

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 135

Registration Number: NCT05113836

Locations: 🇫🇷
Hôpital Bichat, Paris, France

AI for Allograft Diseases Diagnosis and Prognosis After Kidney Transplantation

Withdrawn

Conditions: Kidney Transplantation

First Posted Date: 2021-11-09

Last Posted Date: 2024-10-28

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 1500

Registration Number: NCT05112770

Locations: 🇫🇷
Hôpital Necker-Enfants Malades, Paris, France

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