Postoperative Analgesia in patients of Anterior Cervical Discectomy and Fusion (ACDF) Surgery

Completed

Conditions: Medical and Surgical,

Registration Number: CTRI/2020/12/030091

Lead Sponsor: Dr Tarun Singh

Brief Summary: Comparisonof Ketamine Versus Fentanyl Infusion for Postoperative Analgesia in patientsundergoing Anterior Cervical Discectomy and Fusion (ACDF) surgery as a topic for thesis for award of the degree of Doctor of Medicine (M.D. Anesthesiology) being undertaken as a prospective randomized controlled double blind study comprising of allthe patients admitted to GMCH for anterior cervical discectomy and fusion surgery. A minimum of 82 patients will be randomized into two groups of 41 eachby computer generated random number using Microsoft Excel program.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 82

Inclusion Criteria

Patients of ASA physical status I and II, aged 18 to 65 years with of BMI <30 with cervical disc prolapse scheduled for single or multiple level anterior cervical discectomy and fusion.

Exclusion Criteria

Patients who have traumatic cervical spine injury, underwent prior cervical disc surgery, prior respiratory compromise, preoperative opioid or steroids use, hypersensitivity to the subject drugs and patients whose mental status will affect the completion of the QoR-15 questionnaire.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of ketamine versus fentanyl infusion for postoperative analgesia in patients undergoing ACDF in terms of:	Intraoperative and 24 hours post operative period
a.Visual Analog Score	Intraoperative and 24 hours post operative period
b. Time to first rescue analgesic	Intraoperative and 24 hours post operative period
c. Number and total dose of rescue analgesic	Intraoperative and 24 hours post operative period

Secondary Outcome Measures

Name	Time	Method
To compare:	a.Degree of overall satisfaction using quality of recovery score (QoR score).

Trial Locations

Locations (1): Geetanjali Medical College and Hospital
🇮🇳
Udaipur, RAJASTHAN, India
Geetanjali Medical College and Hospital
🇮🇳Udaipur, RAJASTHAN, India
Dr Sunanda Gupta
Principal investigator
02942500000
sunandagupta@hotmail.com