Effects of Goal-Directed Fluid Therapy Guided by Inferior Vena Cava Collapsibility Index on Hemodynamics and Enhanced Recovery in Patients Undergoing Lower Limb Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 52
- 主要终点
- Mean Arterial Blood Pressure
研究概览
简要总结
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
详细描述
To overcome these problems and avoid the complications of over or underhydration, we use the Goal-directed fluid therapy(GDFT) guided by Inferior vena cava(IVC) collapsibility index approach in which dynamic parameters of volume responsiveness as a guide for fluid therapy. This will ensure that the fluids given were deficient from the circulation and improve the recovery of the patients according to enhanced recovery after surgery(ERAS) protocols.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient's acceptance.
- •Patients planned for elective lower limb surgery under spinal anesthesia.
- •Both sexes
- •Body Mass Index(BMI): <35
- •Age: 21 ~ 65 years
- •American Society of Anesthesiologists(ASA) Physical Status Classification System: Class I & II
- •Duration of surgery 2~3 hours
排除标准
- •Advanced kidney, liver, respiratory or cardiovascular disease.
- •Contraindication for spinal anesthesia.
- •Patients shifted to general anesthesia for any reason.
结局指标
主要结局
Mean Arterial Blood Pressure
时间窗: intraoperatively every 5 minutes
intraoperative mean arterial blood pressure measured in mmHg
Quality of Recovery-40 score(QoR-40)
时间窗: 24 hours postoperative
QoR-40 score ranges from 40 to 200, the higher the score the better the outcome
Heart Rate
时间窗: intraoperatively every 5 minutes
intraoperative heart rate will be continuously monitored and recorded every 5 minutes
Post Anesthesia Care Unit(PACU) Stay
时间窗: 2 hours postoperatively
time spent in PACU after surgery measured in minutes
次要结局
- Total fluid intake during operation(intraoperatively)
- Number of patients that needed Ephedrine or Atropine(intraoperatively)
- Length of hospital stay(the patient will be followed up for 60 days from day of surgery)
- Peripheral perfusion index(Intraoperatively)
研究者
Mahmoud Aboubakr Abdelkader
resident doctor of anesthesia, Intensive Care and Pain Management
Zagazig University