Effects of Goal-Directed Fluid Therapy Guided by Inferior Vena Cava Collapsibility Index on Hemodynamics and Enhanced Recovery in Patients Undergoing Lower Limb Surgeries
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anesthesia
- Sponsor
- Zagazig University
- Enrollment
- 52
- Primary Endpoint
- Mean Arterial Blood Pressure
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
Detailed Description
To overcome these problems and avoid the complications of over or underhydration, we use the Goal-directed fluid therapy(GDFT) guided by Inferior vena cava(IVC) collapsibility index approach in which dynamic parameters of volume responsiveness as a guide for fluid therapy. This will ensure that the fluids given were deficient from the circulation and improve the recovery of the patients according to enhanced recovery after surgery(ERAS) protocols.
Investigators
Mahmoud Aboubakr Abdelkader
resident doctor of anesthesia, Intensive Care and Pain Management
Zagazig University
Eligibility Criteria
Inclusion Criteria
- •Patient's acceptance.
- •Patients planned for elective lower limb surgery under spinal anesthesia.
- •Both sexes
- •Body Mass Index(BMI): \<35
- •Age: 21 \~ 65 years
- •American Society of Anesthesiologists(ASA) Physical Status Classification System: Class I \& II
- •Duration of surgery 2\~3 hours
Exclusion Criteria
- •Advanced kidney, liver, respiratory or cardiovascular disease.
- •Contraindication for spinal anesthesia.
- •Patients shifted to general anesthesia for any reason.
Outcomes
Primary Outcomes
Mean Arterial Blood Pressure
Time Frame: intraoperatively every 5 minutes
intraoperative mean arterial blood pressure measured in mmHg
Quality of Recovery-40 score(QoR-40)
Time Frame: 24 hours postoperative
QoR-40 score ranges from 40 to 200, the higher the score the better the outcome
Heart Rate
Time Frame: intraoperatively every 5 minutes
intraoperative heart rate will be continuously monitored and recorded every 5 minutes
Post Anesthesia Care Unit(PACU) Stay
Time Frame: 2 hours postoperatively
time spent in PACU after surgery measured in minutes
Secondary Outcomes
- Total fluid intake during operation(intraoperatively)
- Number of patients that needed Ephedrine or Atropine(intraoperatively)
- Length of hospital stay(the patient will be followed up for 60 days from day of surgery)
- Peripheral perfusion index(Intraoperatively)