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临床试验/NCT03619070
NCT03619070Unknown不适用

Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation

Universidade Federal do Triangulo Mineiro2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2018年5月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
80
试验地点
2
主要终点
Fatigability

研究概览

简要总结

This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults

详细描述

The resistance training variables manipulation is utilized for maximize the results of resistance training. However it is unclear whether the resistance training variables manipulation modulates the fatigability (i.e. power-duration relationship) and whether this explains the improvement on physical performance (i.e. gait speed, sit-to-stand and timed up and go tests).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Postmenopausal women (>12 months amenorrhea) with age above or equal 50 years old.
  • No hormone therapy or phytoestrogens

排除标准

  • No-drinker alcohol (no alcohol intake whatsoever in their diet);
  • Non- smokers;
  • Hypertensive with uncontrolled blood pressure values;
  • Diabetic with uncontrolled glycemia;
  • Presence of arthropathies;
  • Presence of myopathies;
  • Skeletal musculotendinous disorder.

研究组 & 干预措施

Lower load resistance training (LL)

Experimental

In the LL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and low load (i.e. 30% of 1RM)

干预措施: Resistance training, LL (Other)

Higher load resistance training (HL)

Experimental

In the HL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)

干预措施: Resistance training, HL (Other)

Higher volume resistance training (HVHL)

Experimental

In the HVHL group, postmenopausal women will perform the resistance training with high volume (i.e. six sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)

干预措施: Resistance training, HVHL (Other)

Control group, (CG)

Other

In CG, the postmenopausal women group will not perform exercise

干预措施: Control group, CG (Other)

结局指标

主要结局

Fatigability

时间窗: Changes in fatigability measure (e.g. baseline and after 12 weeks of intervention)

The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree.

次要结局

  • Physical Performance(Changes in physical performance measure (e.g. baseline and after 12 weeks of intervention))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fábio Lera Orsatti

Principal Investigator

Universidade Federal do Triangulo Mineiro

研究点 (2)

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