Effect of nasal administration of brahmi ghritha on cognitive functions and mode of action of nasal medication with Brahmi ghritha
Phase 3
- Registration Number
- CTRI/2020/03/024148
- Lead Sponsor
- Shilpa S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Healthy male volunteers between 20-40 age group with BMI 18.5 â?? 24.9
2. Nasya Arha as per ayurveda texts
3. Healthy volunteers as determined by screening assessments and Principle investigatorâ??s judgement
Exclusion Criteria
1. Known case of Hypersensitivity to nasal medications
2. Persons under regular and frequent medication for any physical or mental illness
3. History of alcoholism, tobacco intake since 6 months
4. Clinically relevant history of disease related to respiratory, gastro intestinal, cardiovascular, neurological, renal, hepatic and hematological systems
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Assessment of cognitive function with Addenbrookes Cognitive Examination - ACE-III Indian English and on 0th day and 7th day of brahmi ghritha nasya <br/ ><br>2.Identification of bacoside A in blood plasma after nasya karma using HPLC method on 7th day of therapy <br/ ><br>Timepoint: 1.Assessment of cognitive function with Addenbrookes Cognitive Examination - ACE-III Indian English and on 0th day and 7th day of brahmi ghritha nasya <br/ ><br>2.Identification of bacoside A in blood plasma after nasya karma using HPLC method on 7th day of therapy <br/ ><br>
- Secondary Outcome Measures
Name Time Method ot applicableTimepoint: Not applicable