NL-OMON51080招募中不适用
Characterization of Inflammatory Cell Subpopulations of the Gut Associated Lymphoid Tissue and Peripheral Lymph Nodes in Inflammatory Bowel Disease - Immunotyping Lymph Nodes in IBD
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 64
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Inclusion criteria inflammatory bowel disease patients:
- •- Age 18-80 years
- •- Additional for aim 1 of METC research protocol: Patients with Crohn's
- •disease undergoing ileocecal resection because of (inflammatory or fibrotic)
- •stenosis or extensive inflammation or therapy refractory disease
- •Inclusion criteria healthy controls
- •- Negative for inflammatory bowel pathologies.
- •- Age 18-80 years.
排除标准
- •Exclusion criteria for inflammatory bowel disease (IBD) patients:
- •- Patients, who are not able to provide informed consent.
- •- History of malignancy
- •- Viral or bacterial infection within the past 4 weeks
- •- Patients using anticoagulant therapy
- •- Present or previous use of systemic corticosteroids less than 28 days before
- •- Present or previous use of general immunosuppressive agents (e.g.
- •Azathioprine, Methotrexate, Mycophenolate Mofetil)
- •Exclusion criteria healthy controls:
- •- Presence of bowel complaints or other intestinal inflammatory conditions
- •(e.g. diverticulitis)
- •- Individuals using anticoagulant therapy
- •- Present or previous use of systemic glucocorticoids less than 28 days before
- •- Present or previous use of experimental drugs
- •- Present or previous treatment with any cell depleting therapies, including
- •investigational agents
- •- Presence of any disease for which study subjects need chronic or intermittent
- •immunosuppressive therapy (e.g. prednisolone).
- •- History of chronic viral infection
- •- Recent (<1 week) bacterial or viral infection
- •- History of autoimmune disease
- •- History of malignancy
- •- Individuals, who are not able to provide informed consent
研究者
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