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临床试验/ACTRN12619001168145
ACTRN12619001168145尚未招募3 期

Randomised control trial assessing impact of 24-hr post-operative lidocaine infusion vs placebo on return of gastrointestinal function in adults undergoing elective laparoscopic colorectal resections.

Dr Rebecca Shine0 个研究点目标入组 60 人开始时间: 2019年8月20日最近更新:
适应症

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Treatment
盲法
Blinded (masking used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • INCLUSION CRITERIA
  • All patients >18 years undergoing elective laparoscopic/hybrid colorectal resections for benign or malignant conditions at Austin hospital during the study period.

排除标准

  • Contraindications to IV lidocaine:
  • Known history of allergy or hypersensitivity to Lidocaine (lignocaine) or other amide-type local anaesthetic.
  • Stokes-Adams syndrome or any type of heart block or other high-risk arrhythmias.
  • Severe shock
  • Myasthenia gravis
  • Serious diseases of the CNS or of the spinal cord
  • Other exclusion criteria:
  • Childs Pugh A or worse liver disease
  • CKD with eGFR <40ml/hr
  • Chronic use of opioid analgesia or local anesthetics
  • Patients will be excluded if they were unable to participate in postoperative assessments because of language difficulty, postoperative confusion, or cognitive impairment.

研究者

发起方
Dr Rebecca Shine

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