To compare the efficacy of two combination therapies against carbapenem resistant enterobacteriaceaeMeropenem plus colistin versus high dose tigecycline plus colistin in critically ill patients.

Department of Anaesthesiology and Critical and Care Jawaharlal Nehru Medical College AMU Aligarh0 sites0 target enrollmentTBD

ConditionsHealth Condition 1: R799- Abnormal finding of blood chemistry, unspecified

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Health Condition 1: R799- Abnormal finding of blood chemistry, unspecified
Sponsor: Department of Anaesthesiology and Critical and Care Jawaharlal Nehru Medical College AMU Aligarh
Status: Not yet recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

3 years ago

Study Type

Interventional

Investigators

Sponsor

Department of Anaesthesiology and Critical and Care Jawaharlal Nehru Medical College AMU Aligarh

Eligibility Criteria

Inclusion Criteria

•1\.Patient having sepsis and SOFA score of 2 or more than 2 at the time of admission in icu/ccw.
•2\.There should be an isolates of carbapenem resistant enterobacteriaceae (CRE) positive either from Blood, tracheal aspirates, urine or abdominal pus culture.
•3\.Patient on any empirical antibiotics except current combination therapy .

Exclusion Criteria

•1\.Patient who is not having sepsis and having SOFA score of less than 2\. Non Carbapenem resistant enterobacteriaceae (CRE) patients.
•3\.Patient who expire within 48 hours of starting the combination
•4\.Patient having sensitivity to the drug use .
•5\.Covid \-19 positive patients

Outcomes

Primary Outcomes

Not specified

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