Evaluation of topical sylimarin formulation efficacy in prevention of radiotherapy induced skin reactions in breast cancer patients
Phase 3
Recruiting
- Conditions
- Radiodermatitis.Radiodermatitis, unspecified
- Registration Number
- IRCT2016110730760N1
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
Age above 18 years; Breast cancer patients after mastectomy undergoing radiotherapy; X-ray total dose of 50.4 GY
Exclusion criteria: Diabetes; Smoking; Anti inflammatory drugs; Immunosuppressor drugs; Immunodeficiency diseases; Connective tissue diseases
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Radiodermatitis occurrence. Timepoint: 1 week after intervention,2week after intervention,3week after intervention,4week after intervention,5week afterintervention. Method of measurement: NCI CTCAE version 4.03 and Acute Radiation Morbidity Scoring Criteria (RTOG).
- Secondary Outcome Measures
Name Time Method