NL-OMON44716已完成3 期
MEtoclopramide, DExamethasone or Aloxi (palonosetron) for the prevention of delayed chemotherapy-induced nausea and vomiting in moderately emetogenic non-AC-based chemotherapy: the MEDEA trial - MEDEA trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 450
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Patient has been diagnosed with histologically or cytologically confirmed solid cancer
- •* Starting with first cycle of chemotherapy of moderate emetogenic risk, which does not include a combination of anthracycline plus cyclophosphamide
- •* Age * 18
- •* WHO * 1
- •* Patient is able to understand and speak Dutch
排除标准
- •* Patient with nausea and/or vomiting in 48 hours before start of chemotherapy treatment
- •* Patient submitted to concomitant radiotherapy or submitted to radiotherapy 15 days before start of chemotherapy or planned to receive radiotherapy during 8 days after administration of chemotherapy
- •* Patient with concomitant severe comorbidy, such as:
- •o Intestinal obstruction
- •o Active peptic ulcer
- •o Hypercalcemia
- •o Uncontrolled diabetes mellitus
- •o Pheochromocytoma
- •o Tardive dyskinesia
- •o Epilepsia
- •o Active infective diseases
- •o Brain * or leptomeningeal metastases
- •o Psychiatrical disorders
- •o Parkinsonism
- •* Current use of corticosteroids (similar to prednisone * 10 milligrams per day)
- •* Current alcohol abuse
- •* Pregnancy
研究者
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