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Clinical Trials/NCT05016583
NCT05016583
Completed
Not Applicable

Paula Method Muscle Exercises in Patients With Low Anterior Resection Syndrome After Sphincter Sparing Rectal Resection: A Feasibility Study

Hadassah Medical Organization1 site in 1 country10 target enrollmentStarted: October 28, 2021Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
10
Locations
1
Primary Endpoint
Improvement in LARS (Low Anterior Resection Syndrome) Score

Overview

Brief Summary

Sphincter sparing rectal resection surgery, either total mesorectal excision (TME) with a temporary loop ileostomy or partial mesorectal excision (PME), is the mainstay of rectal cancer treatment , however, these treatments are associated with the development of Low anterior resection syndrome (LARS). This syndrome is characterized by a constellation of symptoms such as fecal frequency, urgency and clustering of bowel movements and can lead to fecal and flatus incontinence. There is no gold standard therapy designed to treat the root cause of the problems associated with LARS. Paula Method of exercises, based on the theory that the body has the natural ability to self-heal and that all sphincter muscles in the body affect one another other and thus, exercising one healthy region can positively impact another. The purpose of this study is to evaluate the feasibility of the Paula Method of exercises in patients post sphincter sparing rectal resection surgery with LARS Syndrome.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Over age 18
  • LARS syndrome (LARS score of 21 or higher) up to 24 months post sphincter sparing rectal resection
  • Able to read, understand and communicate in Hebrew

Exclusion Criteria

  • Pregnancy
  • Actively undergoing Chemotherapy or Radiation
  • Other causes of anal incontinence or bowel dysfunction (ex: Irritable Bowel Syndrome)
  • Concurrent performance of other exercise methods
  • Unable or unwilling to perform the Paula exercises

Outcomes

Primary Outcomes

Improvement in LARS (Low Anterior Resection Syndrome) Score

Time Frame: 12 weeks

Decrease of in the LARS Score from baseline measurement to the end of the study measurement. The scale is based on a score of 0-42 . A score of 0-20 indicates the absence of LARS, 21-29- Minor LARS, and 30-42- Major LARS.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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