Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in Chronic Obstructive Pulmonary Disease

China-Japan Friendship Hospital1 site in 1 country30 target enrollmentMarch 20, 2024

ConditionsChronic Obstructive Pulmonary Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Chronic Obstructive Pulmonary Disease
Sponsor: China-Japan Friendship Hospital
Enrollment: 30
Locations: 1
Primary Endpoint: Number of Patients completed bronchoscope.
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are:

Can human lung stem cell proliferate in vitro.
Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Registry

clinicaltrials.gov

Start Date

March 20, 2024

End Date

December 31, 2025

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

China-Japan Friendship Hospital

Responsible Party

Principal Investigator

Gang Hou

Principal Investigator

China-Japan Friendship Hospital

Eligibility Criteria

Inclusion Criteria

•Age under 55, regardless of gender
•Patients with COPD lung disease who are going to undergo bronchoscopic biopsy
•No genetic diseases and other respiratory diseases

Exclusion Criteria

•Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases