Perioperative Outcomes of Anatomic Lung Resections in Patients Who Recovered From Coronavirus Disease 2019 (COVID-19): a Two-Year Retrospective Case Series
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Major complication rate
Study Overview
Brief Summary
This study will determine the outcomes of anatomic lung resections in patients who recovered from coronavirus disease 2019 (COVID-19) disease by describing the morbidity and mortality as well as the length of postoperative hospital stay.
Detailed Description
This study will be conducted at the Lung Center of the Philippines. The study design is a retrospective case series implemented via chart review. Online and written patient records will be reviewed to determine the baseline patient characteristics and the preoperative outcomes. Patients who recovered from COVID-19 will be selected from those who underwent anatomic lung resection from June 1, 2020 to May 31, 2022. This study will be done in accordance with the Helsinky Declaration and Good Clinical Practice Guidelines, and will be subject for approval of the institutional Ethics and Technical Review Boards. Descriptive statistics will be used to describe patient characteristics and perioperative outcomes.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •underwent anatomic lung resection
- •previous COVID-19 infection documented by nasopharyngeal swab RT-PCR or GeneXpert
- •with negative nasopharyngeal swab RT-PCR or GeneXpert prior to lung resection
Exclusion Criteria
- •with incomplete patient records
Outcomes
Primary Outcomes
Major complication rate
Time Frame: perioperative period (up to 30 days after anatomic lung resection)
proportion of patients who develop acute kidney injury, acute myocardial infarction, acute respiratory distress syndrome (ARDS), acute respiratory failure, atelectasis requiring intervention, bronchopleural fistula, empyema thoracis, hemothorax, pneumonia, stroke or venous thromboembolism
Minor complication rate
Time Frame: perioperative period (within 30 days after anatomic lung resection)
proportion of patients who develop atrial fibrillation, pneumothorax or prolonged air leak
Length of postoperative hospital stay
Time Frame: perioperative period (up to 30 days after anatomic lung resection)
time duration from surgery to discharge order
Mortality rate
Time Frame: perioperative period (up to 30 days after anatomic lung resection)
proportion of patients who died due to perioperative complications
Secondary Outcomes
No secondary outcomes reported
Investigators
Alexander H. Tuliao
Medical Officer III
Lung Center of the Philippines