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Oxygen Reserve Index in Different Fresh Gas Flow

Completed
Conditions
Oxygen Reserve Index
Registration Number
NCT06649279
Lead Sponsor
Sakarya University
Brief Summary

Our primary objective is to determine whether oxygen reserve index ORI can be a reliable and sensitive indicator of hypoxia and hyperoxia in low-flow anesthesia settings. Our secondary objective is to investigate the ORI changes during preoxygenation stage.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
64
Inclusion Criteria
  • ASA I-III patients
  • 18-75 years old
  • underwent general anesthesia
  • elective ear, nose and throat surgery, lasting longer than 60 minutes
Exclusion Criteria
  • who did not consent to participate,
  • those with finger deformities
  • unregulated diabetes mellitus, severe heart, kidney, or liver failure, sensitivities to local anesthetics or opioids, those who were morbidly obese (BMI >40 kg/m²), and breastfeeding women.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Oxygen Reserve Index ValueFor each patient, from preoxygenation stage to the end of the general anesthesia

The Oxygen Reserve Index (ORI) is a real-time monitoring measure that captures the oxygen reserve status in the moderate hyperoxic range (PaO2 approximately 100 to 200 mmHg). ORI provides early warning of potential oxygenation disturbances before any changes occur in SpO2 and indicates the response to oxygen therapy. ORI ranges from 1 (high reserve) to 0 (no reserve) and measures changes in mixed venous oxygen saturation (SvO2) optically after arterial oxygen saturation reaches 100%.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Sakarya University Training and Research Hospital

🇹🇷

Sakarya, Turkey

Sakarya University Training and Research Hospital
🇹🇷Sakarya, Turkey
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