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The hyperbaric oxygen therapy in the sudden hearing loss of unknown origi

Conditions
Sudden Sensorineural Hearing Loss
Therapeutic area: Diseases [C] - Ear, nose and throat diseases [C09]
Registration Number
EUCTR2013-003268-29-IT
Lead Sponsor
AUSL Piacenza
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

-age > 18 yrs
-unilateral sensorineural hearing loss appeared in less than 72 hrs
-hearing threshold equal or greater than 30 dB at three or more adjacent frequencies
-therapy starting maximum 7 days after the symptoms appearance
-signed informed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 160
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 80

Exclusion Criteria

-Middle ear disease
-Previous sudden hearing loss (relapsing hearing loss)
-Definite diagnosis (definite viral infection, Meniere’s disease, acoustic neuroma, ototoxyc drugs, multiple sclerosys)
-High embolic risk from cardiac or vascular diseases
-HOT contraindications (pneumotorax, upper respiratory tract infections, seizures, chemotherapy, psycosis)
-Diabetes
-Gastric ulcer
-Pregnancy
-No informed consent

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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