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PASSAGE Clinical Trial

Not Applicable
Recruiting
Conditions
nresectable malignant gastric outlet obstruction
Registration Number
JPRN-jRCT2032220496
Lead Sponsor
Kawahara Kazuo
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
51
Inclusion Criteria

Unresectable malignant duodenal obstruction confirmed by biopsy
Eligible for endoscopic intervention
GOOSS score of 0 or 1
18 years of age or older
Willing and able to comply with the study procedures or legally authorized representative (LAR) must provide written informed consent form (ICF) to participate in the study

Exclusion Criteria

Exclusion Criteria at informed consent
Prior metallic stent placement for GOO
Contraindicated to surgery and general anesthesia
Neoplasm invading the target site of puncture in gastric and/or jejunum
Altered anatomy of the upper gastrointestinal tract due to surgery of esophagus, stomach and duodenum that might preclude endoscopic drainage
Presence of ileus caused by peritoneal carcinomatosis, or expected to present within 30 days post procedure
Intervening gastric varices or vessels at the target site of stent insertion
Ascites that may interfere the safety of the index procedure
Subject is currently participating, or plans to participate in, another investigational trial that may confound the results of this trial (unless written approval is received from the Boston Scientific study team)
Vulnerable subject

Exclusion Criteria at the index procedure
Guidewire does not cross the area of GOO
EP-DB does not advance to the target site in jejunum
The distance between the gastric wall and jejunal wall when visualized on ultrasound after saline is introduced into the space between the two inflated balloons of EP-DB is deemed about 2 cm or more

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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