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An Extend Comparative Study Of Swetaparpati And Gokshurpunarnavadi Yoga In The Treatment Of The Renal Stone.

Phase 2/3
Completed
Conditions
Calculus of kidney. Ayurveda Condition: ASMARI, (2) ICD-10 Condition: N200||Calculus of kidney. Ayurveda Condition: ASMARI,
Registration Number
CTRI/2023/06/053490
Lead Sponsor
GOVERNMENT AKHANDANAD AYURVED COLLEGE
Brief Summary

An extended comparative clinical study of swetaparpati and gokshurapunarnavadi yoga (anubhut) in the management of renal stone(vrikkashmari)

 Introduction

Ashmari comprises of two words, I.e.Ashma means a stone and Ari means Enemy.

Ashmari is a disease in which there isformation of stone , resulting into severe pain as given by enemy. As perShusruta samhita Ashmari is included in Ashtomahagada (Eight dreadful disease)due to It’s notorious nature and reluctant to cure.

 In western medical science,the best possibletreatment for urinary calculus are use of certain medicine including variousdiuretic as well as surgical intervention which in Closed and Opensurgery,PCNL,ESWL,URS etc. However all this method have high chances ofrecurrence due to its peculiar tendency and it is also an expensive affair,evenafter surgery patients have to take medicine to check it is further recurrence.Therefore it is necessary to find out an economical, effective, easilyavailable and acceptable medicine to treat RENAL STONE.

 Hence in this present clinical study, Sweta parpati& Gokshurapunarnavadi yoga are selected for the management of Vrikkashamri.

 Research question

Whether Gokshurapunarnavadi yoga (anubhuta) is moreeffective than Sweta parpati (s.y.s) in the management of RENAL STONE or not?

 Hypothesis

Null Hypothesis (H0): There is no difference in theeffect of Swetaparpati and Gokshurapunarnavadi yoga in the management of RENALSTONE.

Alternative Hypothesis (H1): Sweta parparti is moreeffective than Gokshurpunarnavadi yoga in the management of RENAL STONE.

Alternative Hypothesis (H2): Gokshurpunarnavadiyoga is more effective than Sweta parpati in the management of RENALSTONE.

 Aim

To compare the clinical effect of Sweta parpati andGokshurapunarnavadi yoga in the management of RENAL STONE.

 Objectives

1.To evaluate the clinical efficacy of Swetaparpati and Gokshurapunarnavadi yoga in the management of RENAL STONE.

2.To understand the pathophysiology of RENALSTONE from Ayurvedic as well as modern point of Views.

 Drug review

Group A (Control group):- Swetaparpati (s.y.s) withcoconut water (Acidic) for 30 days

No. Of patient:20

Route:Orally

Dose:1gm

Time(Aftermeal):Twice a day

Duration:30 days

 GroupB (Trial group) :-Gokshurapunarnavadi churna (Anubhutyoga) with soda water for30 days

No. Of patient:20

Route:Orally

Dose:3gm

Time(Aftermeal):Twice a day

Duration:30 days

 Diagnostic criteria

1. Subjective criteria:

- Flank pain

- Nausea

- Vomiting

- Sweating

2.Objective criteria

     

- Rakta mootrata

- Size of calculus by USG

- Number of calculus by USG

 Follow up:

After completion of treatment for 1 month,allthe patients to be instructed to visit for regular Follow up at seven daysinterval for the period of 1 month.

 PATHYA-APATHYA:

Written Pathya-Apathya chart will beprovided to patients as per classical texts.

 Benifits:

 Project will help us to solve researchquestion.Whether Gokshurpunarnavadi yoga is more effective than Sweatparpati inthe management of Renal stone or not. Collected information from this projectwill be kept confidential, all outcomes will be noted in tabular form andappropriate statistical tests will be applied.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
40
Inclusion Criteria
  • 1.Age Group Between 18 to 60 Years.
  • 2.Patients Presented with classical symptoms of RENAL STONE.(Flank pain,Nausea,Vomiting,Sweating,Haematuria) 3.Patients having Calculus size upto 10mm.
  • 4.After Surgery (One Side Nephrectomy) Patient having one kidney.
Exclusion Criteria
  • 1.Patients below 18years and above 60years to be excluded from the study.
  • 2.Patients having calculus size more than 10mm.
  • 3.Uncontrolled Diabetes (HbA1c>6.5) and Hypertension(more than 150/90mmhg).
  • 4.Patients With Obstructive Pathogenesis like BPH,Urethrel Stricture etc.
  • 5.Patients associated with Complications like Pyonephrosis,Gross Hydronephrosis,Gross Hydroureter,CRF.
  • 6.Known Cases of Malignancy.
  • 7.Severe Systemic diasease like TB,HIV ETC.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1)Assess Reduce Stone Size4 Weeks
2)Assess Relief in Symptomps4 Weeks
Secondary Outcome Measures
NameTimeMethod
To Assess Improve Of Quality Of Life4 Weeks

Trial Locations

Locations (1)

Government Akhandanand Ayurveda Hospital

🇮🇳

Ahmadabad, GUJARAT, India

Government Akhandanand Ayurveda Hospital
🇮🇳Ahmadabad, GUJARAT, India
Dipa Kanani
Principal investigator
9687353123
knanidipa17@gmail.com

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