A cohort study on the pathogenesis and physical basis of idiopathic membranous nephropathy
Phase 1
Recruiting
- Conditions
- Idiopathic membranous nephropathy
- Registration Number
- ITMCTR2000003385
- Lead Sponsor
- Guangdong Provincial Hospital of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Patients aged 18-85 years;
2. Patients with renal biopsy consistent with IMN diagnosis;
3. Serum PLA2R antibody was positive and no secondary factors were found.
Exclusion Criteria
1. Patients with glomerular filtration rate less than 15 ml / min;
2. Patients with active malignant tumor;
3. Patients with severe primary diseases such as decompensated cirrhosis or hemopoietic system;
4. Psychopaths.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite remission rate (complete or partial remission);
- Secondary Outcome Measures
Name Time Method Total serum protein;Partial remission rate;Serum albumin;PLA2R antibody;uric acid;Serum creatinine;Glomerular filtration rate;White blood cell;Complete remission rate;blood platelet;serum potassium;blood glucose;triglyceride;Urine protein creatinine ratio;cholesterol;hemoglobin;Red blood cell;24-hour urinary protein;LDL;