Study of the Personal Identity in Adults With Autism Spectrum Disorder Without Intellectual Deficiency
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 102
- 试验地点
- 2
- 主要终点
- The number of details in the memory (A)/The specificity of the memory (B)
研究概览
简要总结
The research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subjects to tell autobiographical memories and to specify their characteristics by answering focused questions. In the second study (Study B), the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements.
详细描述
Introduction:
Autism associates impairments in social relationships and specific competencies linked to restricted interests. These interests usually focus on mathematics, drawings or foreign language learning and are very significant in the autobiographies of persons with autism without intellectual deficiency. It's seem to be a basement of their self-identity. The personal identity relies on both the self representations and the sense of self. This sense of self supports the self continuity through time which links the present feelings, the autobiographical memories and the future personals projects. The personal identity depends on the memory of life events called "autobiographical memory."
Objectives:
The research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subjects to tell autobiographical memories and to specify their characteristics by answering focused questions. In the second study (Study B), the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements.
Expected Results:
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Study A & B, Adults with autism spectrum disorders without intellectual deficiency
- •Inclusion criteria:
- •adults with autism spectrum disorders
- •18 to 65 years old
排除标准
- •treatment with benzodiazepines
- •Study A & B, control adults
- •Inclusion criteria:
- •healthy volunteers
- •18 to 65 years old
- •Exclusion criteria:
- •psychiatric disorders
研究组 & 干预措施
Autism spectrum disorder studyA part1
The subjects will perform clinical, psychological and neuropsychological assessment. the subjects will do 3 tests about executive functions. Finally, the participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.
Autism spectrum disorder studyA part2
The subjects will perform Autobiographical memories Assessment. The subjects will tell autobiographical memories freely first and secondly by answering focused questions to specify the characteristics of subjects' memories
干预措施: Autobiographical memories Assessment (Other)
Control adults Study A, part 1
The subjects will perform clinical, psychological and neuropsychological assessment. The subjects will do 3 tests about executive functions. The participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.
干预措施: clinical, psychological and neuropsychological assessment (Other)
Control adults Study A, part 2
The subjects will perform Autobiographical memories Assessment. The subjects will tell autobiographical memories freely first and secondly by answering focused questions to specify the characteristics of subjects' memories
干预措施: Autobiographical memories Assessment (Other)
Autism spectrum disorder Study B, part 1
The subjects will perform clinical, psychological and neuropsychological assessment. The subjects will do 3 tests about executive functions. The participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.
干预措施: clinical, psychological and neuropsychological assessment (Other)
Autism spectrum disorder Study B, part 2
The subjects will perform Autobiographical memories assessment characteristics. The subjects will say the self statements which define them. Then, the participants will have to tell and specify the characteristics of the autobiographical memories linked to the self statements.
干预措施: Autobiographical memories assessment characteristics (Other)
Control adults, Study B part 1
The subjects will perform clinical, psychological and neuropsychological assessment.The subjects will do 3 tests about executive functions. Finally, the participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.
干预措施: clinical, psychological and neuropsychological assessment (Other)
Control adults, Study B part 2
The subjects will perform Autobiographical memories assessment characteristics. The subjects will say the self statements which define them. Then, the participants will have to tell and specify the characteristics of the autobiographical memories linked to the self statements
干预措施: Autobiographical memories assessment characteristics (Other)
结局指标
主要结局
The number of details in the memory (A)/The specificity of the memory (B)
时间窗: The number of details or the specificity of the memory is assessed from 1 day to 3 months after the inclusion/baseline
study A:The number of details is the total number of perceptual/sensory, temporal, contextual, emotional and cognitive details found in the memory after spontaneous recall first. Secondly, the investigators will ask subjects to clarify the five characteristics of the details presented upper and retrieval should be make easier with specific cueing. Study B:The specificity measures how the memory is focused on specific date, space, context, emotions, thoughts and feelings. The specificity of the memories is deeply linked to the self .
次要结局
- Study Aand B:Executives functions test 2(Executives functions will be assessed during the initiation/baseline visit (V1))
- Study A and B:Executives functions test 3(Executives functions will be assessed during the initiation/baseline visit (V1))
- Study A and B: The self concept, questionnaire 2(self-concept will be assessed during the initiation/baseline visit (V1))
- Study A and B: Autistic symptoms questionnaire 1(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
- Study A and B: Autistic symptoms questionnaire 2(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
- Study A and B:Executives functions, test 1(Executives functions will be assessed during the initiation/baseline visit (V1))
- Study A and B: The self concept, questionnaire 1(self-concept will be assessed during the initiation/baseline visit (V1))
- Study A and B: The self concept, questionnaire 3(self-concept will be assessed during the initiation/baseline visit (V1))
- Study A and B: Autistic symptoms questionnaire 3(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
- Study A: the number of remember/ know/ guess responses, the perspective in recollection and the subjective temporal distance in the memory(This outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1)
- Study B:The importance for the self of the memory test1(This outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
- Study B:The importance for the self of the memory test 4(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
- Study B:The importance for the self of the memory test 2(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
- Study B:The importance for the self of the memory test 3(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)