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Clinical Trials/NCT02747056
NCT02747056
Completed
N/A

Study of the Personal Identity in Adults With Autism Spectrum Disorder Without Intellectual Deficiency

University Hospital, Strasbourg, France1 site in 1 country102 target enrollmentJune 1, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism Spectrum Disorders
Sponsor
University Hospital, Strasbourg, France
Enrollment
102
Locations
1
Primary Endpoint
The number of details in the memory (A)/The specificity of the memory (B)
Status
Completed
Last Updated
4 months ago

Overview

Brief Summary

The research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subjects to tell autobiographical memories and to specify their characteristics by answering focused questions. In the second study (Study B), the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements.

Detailed Description

Introduction: Autism associates impairments in social relationships and specific competencies linked to restricted interests. These interests usually focus on mathematics, drawings or foreign language learning and are very significant in the autobiographies of persons with autism without intellectual deficiency. It's seem to be a basement of their self-identity. The personal identity relies on both the self representations and the sense of self. This sense of self supports the self continuity through time which links the present feelings, the autobiographical memories and the future personals projects. The personal identity depends on the memory of life events called "autobiographical memory." Objectives: The research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subjects to tell autobiographical memories and to specify their characteristics by answering focused questions. In the second study (Study B), the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements. Expected Results: The first study will inform the investigators on the sense of self and self continuity through time. The investigators predict that it would be difficult for subjects with autism spectrum disorders to give details of their life events. The focused questions should make easier the recollection of the memories. The investigators hypothesize that the memories linked to the typically autistic restricted interests would be more detailed. The second study will inform the investigators on the memories linked to self representations. The investigators predict that these memories would be, in autism, less detailed and less important for identity. The investigators also hypothesize that the memories linked to the restricted interests would be more detailed and important for the self. Autobiographical memory and socialization are deeply interconnected. So, the investigators think that this research will help them to elaborate news therapies focused on autobiographical memory improvement. Finally, the investigators want to reduce the social disability in autism.

Registry
clinicaltrials.gov
Start Date
June 1, 2016
End Date
October 11, 2019
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Strasbourg, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

The number of details in the memory (A)/The specificity of the memory (B)

Time Frame: The number of details or the specificity of the memory is assessed from 1 day to 3 months after the inclusion/baseline

study A:The number of details is the total number of perceptual/sensory, temporal, contextual, emotional and cognitive details found in the memory after spontaneous recall first. Secondly, the investigators will ask subjects to clarify the five characteristics of the details presented upper and retrieval should be make easier with specific cueing. Study B:The specificity measures how the memory is focused on specific date, space, context, emotions, thoughts and feelings. The specificity of the memories is deeply linked to the self .

Secondary Outcomes

  • Study Aand B:Executives functions test 2(Executives functions will be assessed during the initiation/baseline visit (V1))
  • Study A and B:Executives functions test 3(Executives functions will be assessed during the initiation/baseline visit (V1))
  • Study A and B: The self concept, questionnaire 2(self-concept will be assessed during the initiation/baseline visit (V1))
  • Study A and B: Autistic symptoms questionnaire 1(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
  • Study A and B: Autistic symptoms questionnaire 2(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
  • Study A and B:Executives functions, test 1(Executives functions will be assessed during the initiation/baseline visit (V1))
  • Study A and B: The self concept, questionnaire 1(self-concept will be assessed during the initiation/baseline visit (V1))
  • Study A and B: The self concept, questionnaire 3(self-concept will be assessed during the initiation/baseline visit (V1))
  • Study A and B: Autistic symptoms questionnaire 3(the Autistic symptoms will be assessed during the initiation/baseline visit at V1)
  • Study A: the number of remember/ know/ guess responses, the perspective in recollection and the subjective temporal distance in the memory(This outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1)
  • Study B:The importance for the self of the memory test1(This outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
  • Study B:The importance for the self of the memory test 4(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
  • Study B:The importance for the self of the memory test 2(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)
  • Study B:The importance for the self of the memory test 3(this outcome will be assessed on the follow up visit (V2) either one day after the inclusion visit (V1) or within 3 months after V1Description)

Study Sites (1)

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