ISRCTN12308164已完成1 期
Clinical efficacy of oral alendronate in ankylosing spondylitis: a randomised placebo-controlled trial
Royal National Hospital for Rheumatic Diseases (UK)0 个研究点目标入组 180 人开始时间: 2015年12月15日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 180
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients had to meet the modified New York criteria for the diagnosis of AS, which we refined to allow for MRI diagnosis of sacroiliitis, and a requirement for a minimum pre-defined movement restriction
- •2. Fulfil ASAS criteria for axial SpA
- •3. Aged over 21 years
- •4. If taking NSAID, have been on a stable dose for at least 4 weeks
- •5. There was no minimal level of disease activity required for entry to the study
排除标准
- •1. Any intervention or underlying disease with the potential to effect disease activity or bone density, including treatment with anti-TNF
- •2. Patients with bilateral hip replacements or previous back surgery that would prevent accurate bone density measurement by dual x-ray absorptiometry (DXA)
研究者
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