The effect of melatonin on post-appendectomy pai

Phase 3

• Conditions: Post-appendectomy pain.; Other acute postprocedural pain; G89.18

• Registration Number: IRCT20220507054763N1
• Lead Sponsor: Vice-Chancellery for Research Hormozgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Age of 18-80 years
ASA class I & II
Candidacy for appendectomy under general anesthesia

Exclusion Criteria

Addiction
Allergy to melatonin
Neurological or psychiatric disease
History of taking analgesics for other reasons

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-appendectomy pain. Timepoint: At 2, 12, and 24 hours after surgery. Method of measurement: Visual analogue scale.

Secondary Outcome Measures

Name	Time	Method
The amount of analgesics required. Timepoint: Up to 24 hours after surgery. Method of measurement: gr pethidine.;Sedation. Timepoint: At 2, 12, and 24 hours after surgery. Method of measurement: Ramsay Sedation Scale (RSS).;Side effects, including hypotension, bradycardia, and respiratory depression. Timepoint: Up to 24 hours after surgery. Method of measurement: Measurement of blood pressure (systolic blood pressure <90 mmHg), heart beat (<60), and respiratory rate (<12).