Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery

Not Applicable

Recruiting

• Conditions: Coronary Artery Bypass Graft Surgery; Coronary Artery Disease

• Registration Number: NCT07006441
• Lead Sponsor: Atlas University

Brief Summary

This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function, peripheral muscle strength, pain, kinesiophobia, and quality of life in patients undergoing coronary artery bypass graft (CABG) surgery. The study aims to determine whether initiating rehabilitation prior to surgery improves short-term postoperative outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-01
• Status Verified: 2025-05
• Study First Submitted: 2025-05-28
• Study First Submitted QC: 2025-05-28
• Last Update Submitted: 2025-05-28
• Study First Posted: 2025-06-05
• Last Update Posted: 2025-06-05
• Primary Completion: 2025-06-30
• Study Completion: 2025-06-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Having undergone coronary artery bypass graft surgery
• Ejection Fraction (EF) > 40%
• Being between the ages of 18-65
• Being able to speak, read and understand in their own language
• Volunteering to participate in the study

Exclusion Criteria

• Having an active or suspected infection
• Presence of an active tumour
• History of thrombophlebitis or pulmonary embolism within the last 3 months
• Having an orthopaedic, neurological or cardiovascular disease that may affect the assessments

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Forced Expiratory Flow 25-75% (FEF25-75)	2 weeks	Forced Expiratory Flow 25-75% will be measured before six-minute walk test according to the guideline of ERS.
6-minute Walk Test	2 weeks	The 6-minute Walk Test will be performed according to ATS guidelines. Walking distance, minute ventilation, respiratory rate, inspiratory capacity and breathing reserve will be recorded.
Forced Vital Capacity (FVC)	2 weeks	Forced Vital Capacity will be measured before six-minute walk test according to the guideline of ERS.
Forced Expiratory Volume in 1 second (FEV1)	2 weeks	Forced Expiratory Volume in 1 second will be measured before six-minute walk test according to the guideline of ERS.
Peak Expiratory Flow (PEF)	2 weeks	Peak Expiratory Flow will be measured before six-minute walk test according to the guideline of ERS.
M. Quadriceps Muscle Strength	2 weeks	The m. quadriceps muscle strength will be measured using the MicroFet 2 hand-held dynamometer (Hogan Health Industries, USA). The test will be repeated three times for the dominant side and the average value in kilograms (kg) will be recorded.
M. Biceps Muscle Strength	2 weeks	The m. biceps muscle strength will be measured using the MicroFet 2 hand-held dynamometer (Hogan Health Industries, USA). The test will be repeated three times for the dominant side and the average value in kilograms (kg) will be recorded.
Cough Peak Flow	2 weeks	Cough Peak Flow (CPF) will be measured using a peak expiratory flow meter. Participants will be instructed to take a maximal deep breath and then cough as forcefully as possible into the device; the highest value from three trials will be recorded in liters per minute (L/min). Measurements will be performed in a seated position, ensuring a tight mouth seal and consistent technique.

Secondary Outcome Measures

Name	Time	Method
Level of Pain	2 weeks	Pain assessment will be performed using the Visual Analog Scale (VAS) to evaluate chest pain levels. Participants will be asked to mark their current pain intensity on a 10 cm horizontal line, with "no pain" at one end and "worst imaginable pain" at the other. The distance in centimeters from the "no pain" end to the mark will be measured and recorded as the pain score.
Level of Fear of Movement	2 weeks	Fear of movement (kinesiophobia) will be assessed using the Tampa Scale for Kinesiophobia (TSK). Participants will complete the 17-item questionnaire, which evaluates fear of movement and re-injury on a 4-point Likert scale. The total score, ranging from 17 to 68, will be calculated, with higher scores indicating greater fear of movement.
Level of Quality of Life	2 weeks	Quality of life will be assessed using the Short Form-36 (SF-36) Health Survey. Participants will complete the 36-item questionnaire, which evaluates eight domains including physical functioning, bodily pain, general health, and mental well-being. Each domain will be scored from 0 to 100, with higher scores indicating better perceived quality of life.

Trial Locations

Locations (1)

Istanbul Atlas University; 🇹🇷 Istanbul, Turkey