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Clinical Trials/NCT02819011
NCT02819011
Completed
Phase 2

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

Bijan Najafi, PhD1 site in 1 country44 target enrollmentMay 2016

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Accidental Falls
Sponsor
Bijan Najafi, PhD
Enrollment
44
Locations
1
Primary Endpoint
Ankle Sway Change From Baseline to 6 Months
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older adults.

Primary Endpoints • Characterize the impact of MBB AFO on balance, gait, risk of falling, frailty status, and adverse events

Secondary Endpoints • Characterize the Impact of MBB AFO on spontaneous daily physical activities • Characterize the feasibility of the MBB AFO device on patient adherence, acceptability, user-friendliness, and perception of benefit for daily usage

Registry
clinicaltrials.gov
Start Date
May 2016
End Date
April 4, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Bijan Najafi, PhD
Responsible Party
Sponsor Investigator
Principal Investigator

Bijan Najafi, PhD

Professor of Surgery

Baylor College of Medicine

Eligibility Criteria

Inclusion Criteria

  • Age 65 or older
  • High concerns or high risk of fall
  • Ambulatory

Exclusion Criteria

  • Presence of an active wound infection on either of the foot and ankle
  • Use of medication or a medical condition that may have unstable (fluctuate over time) or temporary (less than one month) impact on gait and balance
  • Acute fractures on the foot
  • Participant of an interventional study within the last 30 days
  • Non-ambulatory or unable to stand without help or walk a distance of at least 1.8 m (\~six feet) without assistance
  • Major foot amputation
  • Unable or unwilling to participate in all procedures

Outcomes

Primary Outcomes

Ankle Sway Change From Baseline to 6 Months

Time Frame: baseline to 6 months

Ankle sway (motion of ankle joint in three dimensions) measured by wearable inertial sensors while wearing their own shoes compared to the orthopedic shoes and compared to orthopedic shoes plus Ankle-Foot Orthosis (AFO)

Hip Sway Change From Baseline to 6 Months

Time Frame: baseline to 6 months

Hip sway (motion of hip joints in three dimensions) measured by wearable sensors while wearing their own shoes compared to the orthopedic shoes and compared to orthopedic shoes plus Ankle-Foot Orthosis (AFO)

Center of Mass (COM) Sway Change Baseline to 6 Months

Time Frame: baseline to 6 months

Center of Mass (COM) sway measured by wearable inertial sensors while wearing their own shoes compared to the orthopedic shoes and compared to orthopedic shoes plus Ankle-Foot Orthosis (AFO)

Secondary Outcomes

  • Adherence (Hours Per Day to Wear Ankle-Foot Orthosis (AFO))(6 months)
  • Fall Incidents(Baseline, 12 months)
  • Concern for Falling Change Form Baseline to 6 Months(Baseline, 6 months)
  • Physical Activity Level(baseline to 6 months)
  • Number of Participants With Adverse Events(assessed at 1, 3, 6, and 12 months, month 12 reported)
  • Stride Velocity(baseline, 6 months)
  • Stride Time(baseline, 6 months)
  • Percentage of Participants Who Found the Device Useful and Easy to Use(6 months)
  • Stride Length(baseline, 6 months)

Study Sites (1)

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