Early Waning of Maternal Measles and Meningitis C Antibodies
- Conditions
- Measles
- Registration Number
- NCT02219061
- Lead Sponsor
- Guangzhou Center for Disease Control and Prevention
- Brief Summary
Maternal antibodies (measles and meningitis C) may wane in the first six months after birth.
* Geometric mean titers(GMTs) of measles and meningitis C.
* Follow-up on 0 month, 3rd month,5th month and 7th month after birth.
- Detailed Description
Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged \< 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies.
Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- Healthy infants.
- Infants with poor score.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Geometric Mean Titer Up to six months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Guangzhou Center for Disease Control and Prevention
🇨🇳Guangzhou, Guangdong, China