Risk Factors and Disorders Associated With Uterine Adenomyosis Diagnosed on Magnetic Resonance Imaging in Women of Reproductive Age
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Prevalence of Endometriosis in Participants Diagnosed with MRI-Confirmed Adenomyosis
研究概览
简要总结
The goal of this observational case-control study is to identify risk factors and associated conditions related to adenomyosis in women of reproductive age.
The main questions it aims to answer are:
Is there an association between a history of uterine surgery and the occurrence of adenomyosis? Does a higher prevalence of endometriosis or increased number of pregnancies correlate with adenomyosis? Researchers will compare women with MRI-confirmed adenomyosis to a control group of women who underwent pelvic MRI for other reasons but were not diagnosed with adenomyosis to see if there are significant differences in risk factors such as endometriosis, number of pregnancies, and history of uterine surgery.
Participants will:
Undergo pelvic MRI with and without intravenous contrast Provide information on factors such as age, smoking, number of pregnancies, history of uterine surgery, and coexisting conditions like leiomyoma and ovarian cysts This study aims to inform better management strategies for reducing the incidence of adenomyosis by targeting modifiable risk factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- — 至 50 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women of reproductive age (18-50 years).
- •Patients who underwent pelvic MRI for clinical indications.
- •MRI-confirmed diagnosis of adenomyosis (for the case group).
- •Patients without adenomyosis confirmed by MRI (for the control group).
- •Willingness to participate and provide informed consent.
排除标准
- •Women outside the reproductive age range (under 18 or over 50 years).
- •Pregnancy or lactation at the time of MRI.
- •Previous hysterectomy or other major uterine surgeries.
- •Presence of malignancies or other serious conditions that could interfere with the study.
- •Inability to undergo MRI due to contraindications (e.g., metal implants, pacemakers).
- •Incomplete or missing MRI data.
- •Non-consent to participate in the study.
结局指标
主要结局
Prevalence of Endometriosis in Participants Diagnosed with MRI-Confirmed Adenomyosis
时间窗: From admission to discharge, up to 1 week
he presence of endometriosis will be evaluated in participants who have been diagnosed with adenomyosis through pelvic MRI. Diagnosis will be confirmed based on established imaging criteria, including areas of low signal intensity on T2-weighted MRI images. The prevalence will be compared between the case group (women with adenomyosis) and the control group (women without adenomyosis). The outcome will be reported as the percentage of participants in each group diagnosed with endometriosis.
次要结局
未报告次要终点
研究者
Narges Afzali
Clinical Professor
Mashhad University of Medical Sciences