Fall-risk Prevention in Adults Over 65: the Relevance of Morphological and Functional Asymmetries of the Lower Limbs.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Timed Up and Go (TUG) test
研究概览
简要总结
Falls among older adults represent a major public health burden. Approximately 30% of individuals aged 65 and older experience at least one fall each year. These events can lead not only to increased anxiety, depression, and reduced quality of life but also to serious injuries or even death. Key risk factors include muscle weakness, gait disturbances, and balance impairments. Lower limb asymmetry-referring to differences in strength, flexibility, composition, or functional capacity between the two legs-has emerged as a potentially important yet underexplored contributor to fall risk in the elderly population. While asymmetry is frequently studied in the context of sports and physical performance, where it may affect both injury risk and athletic outcomes, its implications for balance and mobility in older adults remain insufficiently investigated. This study aims to examine the relationship between lower limb asymmetries and fall risk, with the goal of identifying predictive indicators and informing the development of more effective fall prevention strategies. Ultimately, a better understanding of this relationship could contribute to improved quality of life for older adults and a reduction in healthcare costs associated with fall-related hospitalizations.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female, of any ethnicity.
- •Age ≥ 65 years.
- •Cognitively intact.
- •Independent ambulation.
- •Signed and accepted informed consent to participate in all procedures required for the study.
排除标准
- •Previous surgical treatments for orthopedic conditions performed within the six months prior to study inclusion.
- •Severe cardiac, pulmonary, or musculoskeletal disorders that may influence the assessment outcomes.
- •Comorbidities associated with increased fall risk, such as Parkinson's disease or stroke.
- •Body Mass Index ≥ 30.
- •Use of medications that affect motor coordination, balance, or bone and muscle metabolism.
- •Active oncological disease.
结局指标
主要结局
Timed Up and Go (TUG) test
时间窗: At baseline
A functional mobility test measuring dynamic balance and gait efficiency. Participants stand up from a chair, walk 3 meters, turn, return, and sit; longer times indicate higher fall risk.
5-Repetition Sit-to-Stand Test (5-rep STS)
时间窗: At baseline
A lower-limb strength and functional performance test. Participants rise from a chair five times as quickly as possible; slower performance reflects reduced strength and increased fall risk.
Balance test
时间窗: At baseline
balance assessment is conducted using Baiobit equipment from BTS Bioengineering. The maximal balance time in monopodalic will be considered (s)
次要结局
- Response time assessment(At baseline)
- Gait Analysis(At baseline)
- Physical Activity Questionnaire (IPAQ)(At baseline)
- Falls Efficacy Scale-International (FES-I)(At baseline)
- SARC-F questionnaire(At baseline)
- fall risk questionnaire (FRQ)(At baseline)
- Dual-energy X-ray absorptiometry (DEXA)(At baseline)
- Strength Assessment(At baseline)
- Power assessment(At baseline)
- High-Density Surface electromyography Assessment (HD-sEMG)(At baseline)
- Dominance test (Step-Up Test)(At baseline)
- Dominance test (Kicking Test)(At baseline)
- Dominance test (Balance Recovery Test)(At baseline)