Trivalent Chromium as a Treatment for Rheumatoid Arthritis Patients
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Arthritis scored by DAS28 score
研究概览
简要总结
Trivalent chromium has shown good results in abolishing inflammation and had a successful result in treating animal model of rheumatoid arthritis. In addition to that, trivalent chromium lacks many side effects which are related to the already known medications of the disease.
So this study aims to evaluate the efficacy of trivalent chromium supplementation in rheumatoid arthritis treatment and measuring the outcomes of that in rheumatoid arthritis patients.
详细描述
Rheumatoid arthritis is a debilitating autoimmune disease which is treated by medications that have many side effects. Trivalent chromium, a naturally occurring element with regulatory effects on blood sugar, has shown anti-inflammatory properties in many studies and has shown a good response at alleviation of rheumatoid arthritis in the disease animal model. For these reasons trivalent chromium should be tried in rheumatoid arthritis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •rheumatoid arthritis
排除标准
- •other autoimmune diseases
研究组 & 干预措施
Trivalent chromium
A dietary supplement already available in market one of its known uses is to control diabetes.
干预措施: Trivalent chromium versus synthetic and/ or biological DMARDs (Drug)
Immunesuppressants
Synthetic and/ or biological DMARDs
干预措施: Trivalent chromium versus synthetic and/ or biological DMARDs (Drug)
结局指标
主要结局
Arthritis scored by DAS28 score
时间窗: three months
DAS 28 is a score of arthritis
ESR in mm/hr
时间窗: three months
lab measures for disease activity
CRP mg/dL
时间窗: three months
lab measures for disease activity
Radiological investigations if required (X-RAY, ultrasound, MRI, bone scan)
时间窗: three months
To assess joints and bone
次要结局
- Serum urea(three months)
- serum creatinine(three months)
- SGOT(three months)
- SGPT(three months)
研究者
Sally Saad Saad Hassouna
Lecturer of Internal Medicine department, Rheumatology and Immunology Unit
Alexandria University