sefulness of Oxygen Reserve Index (ORi), a new parameter of oxygenation reserve potential, for rapid sequence induction of general anesthesia
- Conditions
- Adult patients with ASA (American Society of Anesthesiologists) classification 1 or 2 who are scheduled for surgical procedures under general anesthesia
- Registration Number
- JPRN-UMIN000020983
- Lead Sponsor
- Department of Anesthesiology, Fukushima Medical University
- Brief Summary
Data from 16 of the 20 patients were analyzed. Before oxygen administration, the median SpO2 was 98% (interquartile range[IQR] 97-98) and ORi was 0.00 in all patients. At 3 minutes after starting oxygen administration, the median SpO2 was 100% (IQR 100-100) and the median ORi was 0.50 (IQR 0.42-0.57). There was an SpO2 decline of 1% or more from the peak value after propofol administration in 13 patients, and 32.5 seconds (IQR 18.8-51.3) before the SpO2 decrease, ORi began to decline in 10 of the 13 (77%) patients. The ORi trends enable us to predict oxygenation reduction approximately 30 seconds before SpO2 starts to decline. By monitoring ORi, the incidence related to hypoxemia during rapid sequense induction could be reduced.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
Patients are excluded if they meet any of the following conditions: 1. Under 21 years of age. 2. Impossibility of wearing the sensor due to deformity or hypoperfusion of fingers. 3.cardiac or pulmonary disease (e.g. chronic obstructive pulmonary disease, asthma) 4. Preoperative anemia due to hemoglobinopathies (e.g. sickle cell disease, thalassemia) 5. Ineligibility for participation in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Trends in ORI and SpO2 before and after rapid sequence induction of general anesthesia.
- Secondary Outcome Measures
Name Time Method 1. Basic patient information: Gender, age, height, weight, date of surgery, diagnosis, operative procedure, and sensor attachment site. 2. Presence or absence of adverse events, symptoms, extent, and treatment. 3. Presence or absence of measurement equipment failure. 4. Presence or absence of measurement cessation. 5. Recording of data monitoring: Blood pressure, heart rate, SpO2, SpHb of RootTM, ORI, perfusion index (PI), pleth variability index (PVI), and time from propofol administration to tracheal intubation.