hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical Periodontitis

Not Applicable

Active, not recruiting

• Conditions: Apical Periodontitis; Coronary Artery Disease
• Interventions: Procedure: Endodontic treatment

• Registration Number: NCT06270693
• Lead Sponsor: Postgraduate Institute of Dental Sciences Rohtak

Brief Summary

Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure.

Detailed Description

Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure. Systemic inflammatory burden is assessed before and after endodontic treatment.

Study Timeline

• Study Start: 2022-11-01
• Study First Submitted: 2024-01-13
• Status Verified: 2024-02
• Primary Completion: 2024-02-01
• Study First Submitted QC: 2024-02-13
• Last Update Submitted: 2024-02-13
• Study First Posted: 2024-02-21
• Last Update Posted: 2024-02-21
• Study Completion: 2024-04-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Coronary artery disease patients with and without chronic pulp exposure

Exclusion Criteria

• Other systemic diseases
• Antibiotics for More than 1 month
• Smoking
• Analgesics more than 1 week

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
CAD WITH AP	Endodontic treatment	CORONARY ARTERY DISEASE WITH APICAL PERIODONTITIS

Primary Outcome Measures

Name	Time	Method
Serum hsCRP	12 months	Systemic inflammatory burden assessed
complete hemogram indices	12 months	Systemic inflammatory burden assessed

Secondary Outcome Measures

Name	Time	Method
Periapical index SCORE CHANGE	12 months	1-5 ordinal scale,5 worse outconpme \& HEALING ASSESSED

Trial Locations

Locations (1)

PGIDS; 🇮🇳 Rohtak, Haryana, India