Effect of Endodontic Treatment on Serum High Sensitivity C-reactive Protein and Complete Hemogram Indices in Patients With Cardiovascular Disease With and Without Apical Periodontitis: A Prospective Interventional Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Serum hsCRP
研究概览
简要总结
Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure.
详细描述
Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure. Systemic inflammatory burden is assessed before and after endodontic treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Coronary artery disease patients with and without chronic pulp exposure
排除标准
- •Other systemic diseases
- •Antibiotics for More than 1 month
- •Analgesics more than 1 week
研究组 & 干预措施
CAD WITH AP
CORONARY ARTERY DISEASE WITH APICAL PERIODONTITIS
干预措施: Endodontic treatment (Procedure)
CAD WITHOUT AP
CORONARY ARTERY DISEASE WITHOUT AP
结局指标
主要结局
Serum hsCRP
时间窗: 12 months
Systemic inflammatory burden assessed
complete hemogram indices
时间窗: 12 months
Systemic inflammatory burden assessed
次要结局
- Periapical index SCORE CHANGE(12 months)