Treatment of Atrophic Acne Scars With a Fractional CO2 Laser at 1 Versus 3 Months Intervals

Not Applicable

• Conditions: Atrophic Acne Scars
• Interventions: Procedure: Laser

• Registration Number: NCT01773343
• Lead Sponsor: Aarhus University Hospital

Brief Summary

To compare efficacy and adverse effects of fractional CO2 laser of acne scars treatment with 1 versus 3 months intervals

Detailed Description

Change in scar texture evaluated by blinded evalutaions. Appearance of erythema, oedema, pigmentation, infection after treatment

Study Timeline

• Study Start: 2011-11
• Status Verified: 2013-01
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Study First Submitted: 2013-01-02
• Study First Submitted QC: 2013-01-18
• Last Update Submitted: 2013-01-18
• Study First Posted: 2013-01-23
• Last Update Posted: 2013-01-23

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Have Fitzpatrick skin type I-III. (•Are male or female.
• Are between 18 and 60 years of age.
• Mild to severe acne scarring.
• Are able to read, understand, and sign the Informed Consent.
• Are willing and able to comply with all follow-up requirements -

Exclusion Criteria

• Have had active localized or systemic infections within 6 months of enrollment
• Have compromised ability for wound healing, such as: malnutrition, oral steroid use, history of collagen vascular disease (e.g. lupus, scleroderma, history of keloid formation (raised and thickened scars), atrophic dermatitis (extreme skin irritation or itchiness) or immunologic abnormalities such as vitiligo (white patches of skin due to loss of pigment)
• Have been treated with lasers, chemical procedures, or other cosmetic procedures on the area to be treated within 6 months of enrollment
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CO2 laser at 1 month interval	Laser	CO2 laser treatment of mild to severe acne scars at 1 month interval
CO2 laser at 3 monrths interval	Laser	CO2 laser treatment of mild to severe acne scars at 3 month intervals

Primary Outcome Measures

Name	Time	Method
Change in scar texture	24 weeks

Secondary Outcome Measures

Name	Time	Method
Appearance of erythema, oedema, pigmentation, infection	24 weeks

Trial Locations

Locations (1)

Aarhus University Hospital; 🇩🇰 Aarhus, Aarhus C, Denmark