跳至主要内容
临床试验/NCT03607630
NCT03607630Unknown1 期

Can Imagination Change Upsetting Memories of Trauma?

King's College London1 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2018年8月3日最近更新:
适应症
干预措施

试验速览

阶段
1 期
入组人数
12
试验地点
1
主要终点
Daily Ratings measuring change in Index Memory throughout the project

研究概览

简要总结

Research suggests that imagination is a powerful tool to change images inside our heads (e.g. memories) and make them less upsetting. It is thought that this occurs through changing the meaning attached to the memory (e.g. I am weak), therefore making it less upsetting to remember.

Research has also linked some people's experience of psychosis to distressing trauma memories. Despite this, little is known about whether using imagination to change memories is helpful for people with psychosis. This project will look at whether a talking therapy that uses imagination to change trauma memories helps people with psychosis. This project will specifically look at whether this therapy helps; change the meaning linked to memory, make the memory less upsetting and frequent, and increase sense of control over the memory.

This project will recruit six to twelve people with psychosis. Participants will be recruited from services within South London and the Maudsley NHS Foundation Trust's Psychosis Clinical Academic Group. Participants will first be interviewed about their posttraumatic stress difficulties, experiences of psychosis, mental health, and wellbeing. In this appointment, participants will also identify a traumatic memory to focus on during the talking therapy. Four questions about the trauma memory will be asked every day for the remainder of the project.

Participants will then wait between one to three weeks before they receive three therapy sessions. Comparing participants to themselves for different periods of time makes sure that their memories do not become less upsetting over time, without therapy.

After therapy, participants will continue daily measures for two weeks, with an appointment in the middle (i.e. one week post therapy). This appointment will include questions about posttraumatic stress difficulties, wellbeing and satisfaction with therapy. Participation will last between 6-8 weeks. Participants will be reimbursed for their time

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of a Schizophrenia-spectrum disorder or mood disorder with psychotic features
  • Able to identify an intrusive traumatic memory occurring at least twice in the past week, as assessed by the Post Traumatic Stress Diagnostic Scale.
  • Sufficient English to participate in the project

排除标准

  • Concurrent trauma-focused psychological therapy
  • Primary diagnosis of learning disability, substance use or organic disorder
  • Acute suicide risk
  • Lack of capacity to provide informed consent

研究组 & 干预措施

Waiting Pre-Intervention Control

No Intervention

Participant completes measures for 1-3 weeks (randomly chosen) before they complete the intervention. Participants act as their own controls

Imagery Rescripting

Experimental

3 Sessions of Imagery Rescripting

干预措施: Imagery Rescripting (Other)

结局指标

主要结局

Daily Ratings measuring change in Index Memory throughout the project

时间窗: Daily throughout the project, up to 8 weeks

Change in participant's conviction in the distressing appraisal, frequency, distress, and sense of control associated with the memory

次要结局

  • Client Satisfaction Questionnaire (CSQ-8; Larsen et al, 1979)(One week Post intervention)
  • Credibility and Expectancy Questionnaire (CEQ; Borkovec & Nau, 1972)(First session of therapy, this may be at week 2, 3 or 4, depending upon baseline waitlist time)
  • Change in Wellbeing through 'The Warwick-Edinburgh Mental Well-being Scale' (WEMWBS; Tennant et al, 2007)(First week at Initial assessment and 1 week post therapy)
  • Change in PTSD symptoms through 'The Posttraumatic Diagnostic Scale for DSM-5' (PDS-5; Foa et al., 2016)(First week at Initial assessment and 1 week post therapy)
  • Mini-Trauma and Life Events Checklist (mini-TALE; Hardy et al, in prep)(First week at Initial Assessment)
  • Semi-Structured interview (adapted from Hackmann, Clark ,& McManus's (2000) work on social phobia)(First Week at Initial Assessment)
  • Psychotic Symptom Rating Scales (PSYRATS; Haddock, McCarron, Tarrier, & Faragher, 1999)(First week at the initial assessment)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Can Imagination Change Upsetting Memories of Trauma? | 临床试验