Improving Voice Production for Adults With Age-related Dysphonia
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 220
- 试验地点
- 4
- 主要终点
- Acoustic measure of voice quality (Cepstral Peak Prominence)
研究概览
简要总结
The objectives for this research are to determine the mechanisms by which specific therapy tasks improve voice in age-related dysphonia, and the conditions that limit the extent of improvement. The central hypothesis is that targeted therapy tasks will improve voice, and that severity will determine the extent of improvement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
Participants in the perceptual studies rating audio and visual files will be masked.
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults in age range who volunteer
- •Can understand and complete directions presented in English
- •People with voice disorder associated with advancing age will be included, including bowing, incomplete closure, mild edema, erythema, signs of laryngopharyngeal reflux.
排除标准
- •Laryngeal differences not related to aging (e.g., vocal fold paralysis, moderate-severe edema, lesions, leukoplakia, dysplasia, Parkinson disease)
- •Known history of stroke, brain injury, or other neurological disorder
结局指标
主要结局
Acoustic measure of voice quality (Cepstral Peak Prominence)
时间窗: End of year 3
Perceived voice quality
时间窗: End of year 3
Participants will score the construct of "overall voice quality" using a technique called "sort and rate" in which listeners move icons representing each sound along a line. They align the icons so that best voices are on one side and worst voices are on the other. The distance between the icons represents how much better or worse one sound is than the other. There are no units to the scale. Rankings from all listeners are combined using the statistical technique of multidimensional scaling. The result is a ranked value for each sound file (i.e., voice production) that shows how different they are. There is no highest or lowest value.
Relative glottal gap from laryngeal high-speed videoendoscopy
时间窗: End of year 3
次要结局
- Speed index from laryngeal high-speed videoendoscopy(End of year 3)
- Open quotient from laryngeal high-speed videoendoscopy(End of year 3)
- Fundamental frequency standard deviation from laryngeal high-speed videoendoscopy(End of year 3)
- Maximum area declination ratefrom laryngeal high-speed videoendoscopy(End of year 3)