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Evaluation and comparison between 0.125% vs 0.25% bupivacaine for ultrasound guided sacral erector spinae block in paediatric patients undergoing hypospadias repair.

Phase 3
Completed
Conditions
Hypospadias, unspecified, (2) ICD-10 Condition: N488||Other specified disorders of penis, (3) ICD-10 Condition: N488||Other specified disorders of penis,
Registration Number
CTRI/2023/03/050226
Lead Sponsor
Pt. B.D. Sharma PGIMS Rohtak
Brief Summary

Paediatric male patients aged 8 to 12 yrs with American Society ofAnesthesiologists (ASA) physical status I or II scheduled to undergo surgery for hypospadiasrepair will be included in the study. All children will be evaluated one day prior to surgery. The patients will be instructed on usage of a10mm visual analog scale (VAS) for pain [graded from 0 ( no pain) to 10 ( most severe pain)during preoperative evaluation .From computer generated randomization, patients will be randomly allocated to one of the two groups comprising of thirty patients. Inhalational induction of anaesthesia will be done in a standardized manner to facilitate the placement of supraglottic airway device. Group I (n=30) will be given ultrasound guided sacral erector spinae plane blockwith 1 mlkg-1of 0.125% bupivacaine.2. Group II(n=30) will be given ultrasound guided sacral erector spinae plane blockwith 1 mlkg-1of 0.25% bupivacaine .Pain assessment will be done postoperatively using VAS score at 0 hr, every 15 mins upto 1hr, every half an hour upto 2 hours, 2 hrly upto 12 hours and then at 18th hour and 24th hourpostoperatively. Rescue analgesic will be given at VAS score≥ 4. Patient will be given 15mgkg-1paracetamolinfusion over 10 min but not more frequently than 6 hours. If pain persists after paracetamoladministration, oral ibuprofen 10mgkg-1 will be given but not more frequently than 8 hrs.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
60
Inclusion Criteria

Paediatric male patients aged 8 to 12 yrs with American Society of Anesthesiologists (ASA) physical status I or II scheduled to undergo surgery for hypospadias repair will be included in the study.

Exclusion Criteria

Patients with history of developmental delay, allergic reactions to local anaesthetic infection at the needle insertion site bleeding disorders and on anticoagulants parental refusal shall not be included in the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time for requirement of first rescue analgesicPain assessment will be done postoperatively using VAS score at 0 hr, every 15 mins upto 1 | hr, every half an hour upto 2 hours, 2 hrly upto 12 hours and then at 18th hour and 24 | th hour | postoperatively.
Secondary Outcome Measures
NameTimeMethod
1) Total intraoperative fentanyl consumption2) Post-operative pain score

Trial Locations

Locations (1)

Pt.B.D. Sharma PGIMS ,Rohtak

🇮🇳

Rohtak, HARYANA, India

Pt.B.D. Sharma PGIMS ,Rohtak
🇮🇳Rohtak, HARYANA, India
Dr Bharti Singla
Principal investigator
9009369698
drbhartibs@gmail.com

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