Effects of Multiple Breathing Training on Pulmonary Function and Respiratory Muscle Strength in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Forced Vital Capacity; FVC
研究概览
简要总结
This study were to investigate the effects of multiple breathing training on pulmonary function, respiratory muscle strength, chest expansion, fractional exhaled nitric oxide (FeNO), aerobic capacity, and dyspnea symptoms in older adults.
详细描述
The study included 26 male and female older adults aged 60-75 years, who were divided into a control group (n = 13) that maintained usual daily activities and an experimental group (n = 13) that received multiple breathing training.
The independent variable was multiple breathing training. Dependent variables included lung function (FVC, FEV₁, FEV₁/FVC, MVV), respiratory muscle strength (MIP, MEP), chest expansion, fractional exhaled nitric oxide (FeNO), aerobic capacity, and dyspnea assessment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Older adults aged 60-75 years, both male and female.
- •Not regularly physically active (exercising fewer than 2 times per week) during the 6 months prior to the study.
- •Cooperative, without communication problems, and able to follow instructions from the trainer.
- •No history of cardiovascular disease and no respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), etc.
- •No hypertension, or if diagnosed with hypertension, it must be well controlled, with resting blood pressure not exceeding 140 mmHg systolic and 90 mmHg diastolic.
- •Able to ambulate independently without assistance or assistive devices.
- •Willing to participate in the study and able to provide written informed consent.
排除标准
- •Any unforeseen events preventing continued participation in the study, such as injury from an accident or illness.
- •Attendance of less than 80% of the training sessions (fewer than 19 out of 24 sessions, including the basic training period).
- •Withdrawal of consent or unwillingness to continue participation in the study.
研究组 & 干预措施
Multiple breathing training
The multiple breathing training program consisted of five structured breathing exercises designed to improve inspiratory muscle strength, expiratory muscle strength, and breath control. Each exercise was performed for three sets, and the total training duration was approximately 40 minutes per session.
The program included the following components:
Inspiratory Muscle Training (PowerBreathe device): Participants performed resisted inhalation to strengthen the inspiratory muscles (10 repetitions per set).
Expiratory Muscle Training (Balloon with control device): Participants exhaled into a balloon while maintaining pressure according to their measured maximal expiratory pressure (MEP) (10 repetitions per set).
Inspiratory Training (Tri-Flow device): Participants inhaled through the device to elevate and maintain the floating balls, promoting sustained inspiratory effort (10 repetitions per set).
Expiratory Training (Windmill device): Participants exhaled to rotate the windmill,
干预措施: Multiple breathing training (Other)
Control group (Normal daily life)
结局指标
主要结局
Forced Vital Capacity; FVC
时间窗: Change from Baseline FVC at 8 weeks.
Participants were seated in a chair and wore a nasal clip during the assessment. They first performed three cycles of slow, normal breathing, followed by a demonstration of forced inspiration and expiration, and then returned to normal breathing.
Forced Expiratory Volume in One second; FEV1
时间窗: Change from Baseline FEV1 at 8 weeks.
Participants were seated in a chair and wore a nasal clip during the assessment. They first performed three cycles of slow, normal breathing, followed by a demonstration of forced inspiration and expiration, and then returned to normal breathing.
Maximum Voluntary Ventilation; MVV
时间窗: Change from Baseline MVV at 8 weeks.
Participants were instructed to breathe in and out as quickly and forcefully as possible for 15 seconds.
Maximal Inspiratory Pressure; MIP
时间窗: Change from Baseline MIP at 8 weeks.
Participants were instructed to exhale fully to functional residual capacity (FRC), then place the mouthpiece securely and perform a maximal inspiratory effort sustained for 1-2 seconds.
Maximal expiratory pressure; MEP
时间窗: Change from Baseline MEP at 8 weeks.
Participants inhaled fully to total lung capacity (TLC), maintained a tight seal on the mouthpiece, and then performed a maximal expiratory effort for 1-2 seconds.
次要结局
- Chest expansion(Change from Baseline Chest expansion at 8 weeks.)
- Fraction exhaled nitric oxide; FeNO(Change from Baseline FeNO at 8 weeks.)
- Six minutes walk test (6MWT)(Change from Baseline 6MWT at 8 weeks.)
- The University of California, SanDiego Shorthess of Breath Questionnaire (SOBQ)(Change from Baseline SOBQ at 8 weeks.)
研究者
Wannaporn Tongtako, Ph.D.
Principal investigator
Chulalongkorn University