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A Randomized Controlled Clinical Study on the Effect of Kidney-Tonifying and Blood-Activating Method on IVF-ET Pregnancy Outcomes of Postoperative Infertile Patients with Stage III/IV Endometriosis

Phase 1
Recruiting
Conditions
Infertility
Registration Number
ITMCTR2000003547
Lead Sponsor
Guangdong Provincial Hospital of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

(1) Patients who meet the above-mentioned diagnostic criteria of Chinese and Western medicine, aged 20-38 years old, have been diagnosed with stage III and IV endometriosis through laparoscopic surgery, and are planning to undergo IVF-ET for fertility at a reproductive center;
(2) Have not received traditional Chinese medicine, hormones and similar treatments for at least 3 months before enrollment;
(3) Be able to receive oral treatment with Chinese medicine and voluntarily cooperate with relevant inspections;
(4) Informed consent to this study and signed informed consent form.
(5) Receive random grouping and take drugs according to the study protocol.

Exclusion Criteria

(1) Those with genital tract malformations, uterine submucosal fibroids, and intrauterine adhesions found by hysteroscopy;
(2) Patients with adenomyosis and hydrosalpinx;
(3) The woman whose endocrine test is abnormal;
(4) Other abnormal immune antibodies;
(5) The man with severe oligospermia;
(6) Those who have had immunotherapy or used immune function regulating drugs in the past 3 months;
(7) Those who have a history of autoimmune diseases and/or other medical and surgical diseases;
(8) Patients with cardiovascular and cerebrovascular diseases, severe primary diseases of the liver, kidney, and hematopoietic system and mental illnesses.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Abortion rate;Embryo implantation rate;Live birth rate;Pregnancy rate;Clinical pregnancy rate;
Secondary Outcome Measures
NameTimeMethod
Biochemical factor detection;Endometrial receptivity test;Serum hormone determination;Oocyte and embryo grade evaluation;
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