To Investigate Supplements for Improving Male Sperm Quality and Combating Aging
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Semen analysis
研究概览
简要总结
This study investigates the effects of a new supplement on sperm quality in men with poor sperm quality. Fifty patients will receive the supplement for three months, followed by semen analysis and assessment of sperm aging and mitochondrial function. Changes in sexual function and aging symptoms will also be evaluated.
详细描述
Due to modern lifestyle factors such as high work pressure, stressful routines, and environmental pollution, there has been a significant decline in sperm quality among men, potentially leading to infertility. In response, various supplements have emerged claiming to enhance sperm quality. This prospective investigation aims to determine the efficacy of a new supplement in improving sperm quality among patients with poor sperm quality. The study will enroll 50 patients undergoing semen analysis at our reproductive center, administering the supplement over a three-month treatment period to those identified with poor sperm quality. Subsequent semen analysis will be conducted, alongside assessments of sperm mitochondrial metabolic function before and after supplement administration. Sexual function and aging symptoms will also be evaluated using the International Index of Erectile Function (IIEF-5) and the Aging Males Symptoms Scale (AMS) before and after the supplementation period. The study aims to compare differences in semen analysis, sperm mitochondrial metabolic function, sexual function, and aging symptoms before and after supplementation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Not meet the criteria of the 6th edition of the WHO manual for human semen analysis
- •BMI:18-30 kg/m2
排除标准
- •Azoospermia
- •Varicocele
- •Chromosome anomaly
- •Malignancy
- •Using hormone therapy or supplements in recent 3 months
结局指标
主要结局
Semen analysis
时间窗: through study completion, an average of 1 year
semen concentration, motility and morphology
次要结局
- sexual function(through study completion, an average of 1 year)
- oxygen consumption of mitochondria(through study completion, an average of 1 year)
- mitochondrial function(through study completion, an average of 1 year)
- aging symptoms(through study completion, an average of 1 year)
研究者
Li-Te Lin
Doctor
Kaohsiung Veterans General Hospital.