To examine the effect of dietary supplementation with fish oils and complex lipids on mitochondrial, physical, and cognitive function, in elderly humans.
- Conditions
- veroudering, energiemetabolismeAgeingMetabolism
- Registration Number
- NL-OMON48470
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 108
- Males and females;
- Caucasian;
- Age * 65 years;
- BMI * 20 kg/m2 * 30 kg/m2;
- Normal physical activity levels: maximum of 1 hour per week engagement in
moderate or high intensity structured exercise
- Subject should be in sufficient health to participate in the experiments, to
be judged by the site-specific responsible physician, based on the subject's
medical history.
- Not meeting all inclusion criteria;
- Habitual smoker within the past 5 years;
- Excessive alcohol use (greater than 20g per day) and/or drug abuse;
- Subjects with diagnosed diabetes mellitus type 2;
- Significant food allergies or intolerances concerning the study products,
e.g. cow*s milk protein allergy
- Participation in another biomedical study within 1 month before the first
study visit, possibly interfering with the study results;
- Medication use known to hamper subject*s safety during the study procedures;
- Subjects habitually taking fish oil supplements within 3-months of the
initial study visit or habitually taking lipid supplements that are likely to
affect the main study outcomes;
- Subjects who do not want to be informed about unexpected medical findings;
- Subjects who do not want their treating physician to be informed about
unexpected medical findings;
- Inability to participate and/or complete the required measurements.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method