NCT00249886撤回3 期
Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 撤回
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Relapse - subject meets criteria for an episode of major depression for 2 weeks or more.
研究概览
简要总结
The purpose of the study is to evaluate whether it is advantageous for adolescents who have recovered from depression after a 6 to 12 week course of antidepressant treatment to stay on the treatment a further 6 months or is it just as helpful to stop the medication after recovery.
The hypothesis is that adolescents with major depression who recover from the 6 to 12 week trial of citalopram will be less likely to have a recurrence of depression over a 6 month period if continued on the citalopram as compared to those who discontinue the medication.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 13 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of major Depression.
- •A score of > 16 on the 17 item Hamilton Depression Scale or a score of > 12 on the 17 items plus a score of >7 on the atypical items.
- •Males and females.
- •Outpatient at initiation of double blind treatment phase.
- •Ability to give informed consent.
排除标准
- •Past or current hypomanic or manic episode.
- •Currently meets criteria for a Conduct Disorder.
- •Current psychotic symptoms.
- •Substance dependence in the last 3 months.
- •Significant medical condition that would contraindicate the use of an antidepressant.
- •Pregnancy
- •Past treatment with Citalopram for major depression
结局指标
主要结局
Relapse - subject meets criteria for an episode of major depression for 2 weeks or more.
次要结局
未报告次要终点
研究者
研究点 (2)
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