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临床试验/CTRI/2021/04/033053
CTRI/2021/04/033053已完成不适用

"ASSESSMENT OF EFFICACY OF VIRECHANOTTARA KSHEERAKALYANAKA GHRITA AND JATAMAMSI CHURNA IN THE MANAGEMENTOF ESSENTIALHYPERTENSIONWITH SPECIAL REFERENCE TO UCHCHA RAKTACHAPA.†–A COMPARATIVE STUDY

Dept Of pg studies in kayachikitsa Taranath government ayurvedic medical college and hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2021年4月28日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1
主要终点
Maintenance of Blood pressure to normal level

研究概览

简要总结

Hypertension is a syndrome with elevated blood pressure and modifiable risk factor for cardiovascular, cerebrovascular,renovascular disorders, prevalence increasing at an alarming rate, about 20-24% incidence rate. No direct reference of hypertension is found in ayurvedic texts but the symptoms of diseases like shirahshoola tridoshaja shiroroga unmad vatarakta Raktagata vata Dhamani Pratichaya shleshmavruta vata medoroga show the symptoms of essential hypertension. With a null hypothesis to know the effect of ksheerakalyanaka ghrita which will reduce atherosclerosis peripheral resistance shothahara unmadahara kaphamedahara action is selected. Jatamamsi is a potent aromatic herb known for its tranquilizing anti-convulsive and calming effect. Jatamamsi is Tridoshashamaka shothahara apasmaranashaka murchhahara nidrajanaka and shamaka. So classical drug as well as the single drug show unmadahara effect. Untreated, uncontrolled essential hypertension also mimics unmad. Therefore ksheerakalyanaka ghrita and jatamamsi churna have similar clinical pharmacology acting on Doshanulomana avaranaghna dhatusamyakara and manaprasadana. Hence present study entitled "Assessment of efficacy of Virechanottara ksheerakalyanaka ghrita and jatamamsi churna in the management of essential hypertension with special reference to uchcha raktachapa-A comparative study" is taken.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
30.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients of Essential Hypertension / Stage I Hypertension.
  • Patients between the age group of 30-65 years.

排除标准

  • CCF EF<30% Multiorgan failure Pleural effusion Acute IHD/M.I C.R.F with Sr. Creatinine>8 mg/dl SEPSIS.

结局指标

主要结局

Maintenance of Blood pressure to normal level

时间窗: 6weeks

次要结局

  • Correction of high blood pressure(Improvement in cardiac markers)

研究者

发起方
Dept Of pg studies in kayachikitsa Taranath government ayurvedic medical college and hospital
申办方类型
Government medical college

研究点 (1)

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