Self-estimates and Objective Blood Alcohol Concentration in Emergency Department

Not Applicable

Completed

• Conditions: Alcohol Use Disorder; Blood Alcohol Content
• Interventions: Biological: blood alcohol concentration withdrawal

• Registration Number: NCT03998397
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC). The hypothesis of the study is that self-estimation of BAC by the patient is under-estimated. Moreover, comparing self-estimation of BAC and objective measure of BAC, which is routinely performed in ED, could increase in patients the awareness of the disorders, increase motivation to change of the patient, and increase the rates of seeking-treatment six months after the first evaluation, in particular in patients with alcohol use disorders.

To the investigators knowledge, there is no study investigating self-estimation, compared to objective measurement of blood alcohol concentration in patients with alcohol intoxication presenting to an Emergency Department (ED). The study will assess blood alcohol concentration and self-estimates of BAC, using the Subjective Effects of Alcohol Scale for Measuring Subjective Response to Alcohol in 100 patients with or without alcohol use disorders according to DSM-5 classification (using MINI scale and Alcohol Use Disorders Identification Test (AUDIT)

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-18
• Study First Submitted: 2019-06-21
• Study First Submitted QC: 2019-06-25
• Study First Posted: 2019-06-26
• Primary Completion: 2020-06-18
• Study Completion: 2020-06-18
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-21
• Last Update Posted: 2023-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Patients admitted in Emergency Department while intoxicated will be included in the study, including patients with or without alcohol use disorders according to DSM-5 classification.
• aged 15-64 years old
• patients who will be orally informed and receive a written summary
• blood alcohol concentration of 60mg/dl or higher
• Patients not opposed to participating in the study, who have received an oral and written information

Exclusion Criteria

• Drug intoxication (cannabis, opiates, amphetamines, cocaine), psychotropic medication intoxication (benzodiazepines, antipsychotics), primary neurologic conditions, mental retardation, dementia, amnestic disorders, mental disorders due to a general, medical condition and substance-induced psychotic disorders.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients with alcohol use disorders	blood alcohol concentration withdrawal	-
patients without alcohol use disorders	blood alcohol concentration withdrawal	-

Primary Outcome Measures

Name	Time	Method
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration	Day =0 (day of patient inclusion)	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration

Secondary Outcome Measures

Name	Time	Method
Measure motivation to change six months following the first interview at the Emergency Department	six months following the first interview at the Emergency Department	Measure motivation to change six months following the first interview at the Emergency Department
Measure motivation to change during the first interview at the Emergency Department	Day =0 (day of patient inclusion)	Measure motivation to change during the first interview at the Emergency Department
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient without alcohol use disorders	Day =0 (day of patient inclusion)	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration without alcohol use disorders according DSM-5 classification (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient with alcohol use disorders	Day =0 (day of patient inclusion)	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration with alcohol use disorders according DSM-5 classification (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France