Aggressive Non-Lymphoma and T Helper 2 Cytokines Relationship With Prognostic Markers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Interleukin 4 and Interleukin 10 levels as pg/mL in non hodgkin lymphoma
研究概览
简要总结
The investigators hypothesized that Non Hodgkin lymphoma is using T helper 2 pathways. So that the investigators decided to study of cytokines related to T helper 2 pathways. It is well known that parasites and allergic situations also use T helper 2 pathways. Because that the investigators excluded the patients have parasites and allergic situations. All the patients were over 18. The investigators included the patients with non Hodgkin lymphoma which new diagnosed. It is observational study. The investigators took blood before chemotherapy and four months later. The investigators did not interfere with which chemotherapy will be given to patients. This decision was belong to hematologist or oncologist who will treat the patient.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •newly diagnosed non hodgkin lymphoma
- •Diffuse large B cell lymphoma and T cell lymphoma patients
排除标准
- •under 18 age
- •parasitosis
- •allergic status
结局指标
主要结局
Interleukin 4 and Interleukin 10 levels as pg/mL in non hodgkin lymphoma
时间窗: This study ended within 13 months
We will measure 31 patients and 27 healthy person's Interleukin 4 and Interleukin 10 levels as pg/mL at the beginning of the study. We determined all of the patients IPI score, LDH (U/L), crp (mg/L), erythrocyte sedimentation rate, hemoglobin (gr/dL), lymphocyte count in per µL, albumin (gr/dL) before the treatment. We wanted to check whether there is any correlation between well known prognostic markers (LDH, crp, albumin, stage, ECOG performance status) and Interleukin-4 and interleukin-10 levels.
次要结局
- survey as months(During study which was 13 months)
研究者
Nil Guler
Medical Doctor
Guler, Nil, M.D.