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Clinical Trials/NCT01942499
NCT01942499
Completed
Not Applicable

A Randomized Controlled Trial of a Post-rehabilitation Community-based Exercise Program for Individuals With COPD

West Park Healthcare Centre4 sites in 1 country98 target enrollmentNovember 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
West Park Healthcare Centre
Enrollment
98
Locations
4
Primary Endpoint
Change from baseline in Six Minute Walk Test at 6 months
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

It is well established that individuals living with chronic obstructive pulmonary disease (COPD) demonstrate significant improvements following a formal rehabilitation program. The problem lies in the fact that these functional improvements diminish over a 12 month period. This decline in function is associated with decreased participation, a decline in health status, and an increased need to access the healthcare system. The objective of this project is to evaluate the effectiveness of a post-rehabilitation community-based exercise program for individuals with COPD and compare the outcomes with those achieved through standard care.

Individuals with COPD who have completed a previous rehabilitation program will be enrolled in the study. Study participants will be assigned randomly to either a year-long community exercise program or usual care. Those assigned to the community program will exercise twice weekly at a local community centre supervised by trained fitness instructors. A case manager will facilitate the transition from the hospital rehabilitation program to the community centre. The case manager will also be available to participants and instructors for consult as needed. Continuing to build on an established partnership with the City of Toronto, the case manager will ensure fitness instructors receive specialized training in order to properly supervise and support the individuals with COPD. Participants assigned to usual care group will receive standard care by their family physician and respiratory specialist. Functional status will be evaluated before the program begins and again at 6-months and 1-year. The outcome of each group will be compared to determine the effectiveness of the community exercise program. It is hypothesized that individuals who participate in the community exercise program will have better function and quality of life versus those individuals who receive standard care.

Registry
clinicaltrials.gov
Start Date
November 2012
End Date
July 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Roger Goldstein

Respirologist

West Park Healthcare Centre

Eligibility Criteria

Inclusion Criteria

  • individuals with moderate to severe COPD based on international (GOLD) criteria
  • clinically stable
  • able to provide their own informed consent
  • able to secure independent transportation to the community site

Exclusion Criteria

  • individuals with associated medical conditions that limit their exercise tolerance (cardiovascular, musculo-skeletal, recent surgery, etc.)
  • individuals who report a history of significant cardiovascular disease (i.e. congestive cardiac failure, history of cardiac arrest, acute myocardial infarction within the preceding three months, symptomatic ischaemic cardiac disease, uncontrolled systemic hypertension) or report severe non-respiratory symptoms during exercise
  • individuals receiving mechanical ventilation
  • individuals who are unable to attend the community-based exercise program or follow-up assessment sessions

Outcomes

Primary Outcomes

Change from baseline in Six Minute Walk Test at 6 months

Time Frame: Baseline and 6 months

Change from baseline in Six Minute Walk Test at 12 months

Time Frame: Baseline and 12 months

Secondary Outcomes

  • Change from baseline in Duke Activity Status Index at 12 months(Baseline and 12 months)
  • Change from baseline in Chronic Respiratory Disease Questionnaire at 6 months(Baseline and 6 months)
  • Change from baseline in Repeated Chair Stand at 6 months(Baseline and 6 months)
  • Change from baseline in Duke Activity Status Index at 6 months(Baseline and 6 months)
  • Change from baseline in Repeated Chair Stand at 12 months(Baseline and 12 months)
  • Change from baseline in Health Utilities Index at 6 months(Baseline and 6 months)
  • Change in baseline in COPD Self-Efficacy Scale at 6 months(Baseline and 6 months)
  • Change from baseline in Chronic Respiratory Disease Questionnaire at 12 months(Baseline and 12 months)
  • Change from baseline in Health Utilities Index at 12 months(Baseline and 12 months)
  • Change in baseline in COPD Self-Efficacy Scale at 12 months(Baseline and 12 months)

Study Sites (4)

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