A comparative evaluation between giving Dexamethasone in aerosol form and Magnesium sulphate in aerosol form and assessing whether it prevents post operative sore throat in patients undergoing surgeries in prone position. A prospective randomized double blind study.
Not Applicable
- Conditions
- Health Condition 1: M498- Spondylopathy in diseases classified elsewhere
- Registration Number
- CTRI/2019/05/019262
- Lead Sponsor
- Pondicherry institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.American society of Anesthesiologists (ASA) physical status 1 (normal healthy patient ) and ASA 2 (patient with mild systemic disease )
2. Age between 20 to 60 years
3. Surgeries in prone position under general anaesthesia
4. Duration of surgery less than 3 hours
Exclusion Criteria
1.Patients having history of preoperative sore throat or recent upper airway infection ,asthma ,chronic obstructive pulmonary disease
2.Pregnant woman
3.Mallampati grade > II ( anticipated difficult airway )
4.Known allergies to study drug
5.Patients on chronic medication (NSAID,STEROIDS)
6.Those who require more than one attempt at intubation or traumatic intubation
7.Known smoker
8.Time of intubation > 60 seconds
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of nebulised dexamethasone vs nebulised magnesium sulphate on the incidence of post operative sore throat in prone position surgeriesTimepoint: sore throat will be assessed at immediate post op , after 4 hours, 6 hours, and 24 hours
- Secondary Outcome Measures
Name Time Method To grade the severity of POST between the two groups <br/ ><br> <br/ ><br>To compare haemodynamic profiles between the two groups <br/ ><br> <br/ ><br>Timepoint: INTRAOPERATIVELY AT THE TIME OF INTUBATION , 5 MINUTES AFTER INTUBATION , 10 MINUTES AND 15 MINUTES AFTER INTUBATION RESPECTIVELY