Use of Bedside Lung Ultrasound to Monitor Lung Recruitment Maneuvers During Mechanical Ventilation in Obese Patients

The global escalation of obesity creates distinct challenges for respiratory management in the ICU. In the morbidly obese population, increased chest wall mass and cranial displacement of the diaphragm significantly elevate pleural pressure. This physiological burden leads to widespread atelectasis in dependent lung zones and a marked reduction in functional residual capacity, resulting in a cycle of atelectrauma and severe ventilation-perfusion mismatch. Traditional monitoring tools are inadequate for managing these patients: chest X-rays lack sensitivity for detecting posterior, dependent-zone collapse, Computed Tomography (CT) carries prohibitive transport risks and radiation exposure, and conventional compliance curves provide only global information that obscures regional heterogeneity. Bedside Lung Ultrasound (LUS) offers a paradigm shift by enabling real-time regional visualization of sub-pleural pathology, allowing clinicians to identify the transition from tissue-like consolidation to normal aeration at the bedside.

This study aims to evaluate the clinical utility of bedside LUS as a real-time, radiation-free monitoring tool for assessing the effectiveness of Lung Recruitment Maneuvers (LRMs) and guiding optimal Positive End-Expiratory Pressure (PEEP) titration in mechanically ventilated obese adults.

Study Procedures:

• Baseline Assessment: Following enrollment, baseline ventilator parameters, hemodynamics, Arterial Blood Gas (ABG), static lung compliance, and driving pressure are recorded. A standardized 12-zone LUS scan is performed. Each zone is scored from 0 (A-lines predominant/normal aeration) to 3 (tissue-like consolidation/complete collapse) to calculate a total baseline LUS score.
• Pre-Maneuver Checkpoint: Prior to initiating the maneuver, strict hemodynamic safety criteria must be confirmed, including a Mean Arterial Pressure (MAP) ≥ 65 mmHg, Heart Rate between 60-120 bpm, and SpO₂ ≥ 85%.
• Stepwise Recruitment Maneuver: Ventilation is switched to Pressure Control (PCV) with a constant driving pressure of 15 cmH₂O. PEEP is systematically increased in 2 cmH₂O increments from 10 to a peak of 20 cmH₂O, holding each step for 5 minutes. During each step, a focused 2-zone posterior-basal LUS scan is performed bilaterally.
• Decremental PEEP Titration: Following peak recruitment, PEEP is reduced by 2 cmH₂O every 5 minutes. A focused 4-zone posterior LUS scan is performed at each step to identify the "Closing Pressure," which is the exact PEEP level where B-lines or consolidation reappear in previously aerated zones. Optimal PEEP is calculated as the Closing Pressure plus 2 cmH₂O. A brief re-recruitment is performed before setting this final optimal PEEP.
• Post-Maneuver Assessment: At 15-20 minutes after establishing the optimal PEEP, a full 12-zone LUS scan is repeated to calculate the post-maneuver score. Follow-up ABG, static compliance, driving pressure, and hemodynamic measurements are also recorded.

Scanning is performed by the same trained investigator throughout the study to reduce inter-observer variability, and safety stop criteria are in place to abort the maneuver if patients exhibit severe desaturation, hemodynamic instability, or signs of pneumothorax.