A Predictive Score Identifies Patients With Inadequate Bowel Preparation for Colonoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 605
- 试验地点
- 2
- 主要终点
- Adequate bowel preparation quality at the time of colonoscopy defined by Ottawa score<6
研究概览
简要总结
Colonoscopy is the current standard method for evaluating the colorectal diseases. Adequate bowel preparation is essential for optimal visualization of the colorectal mucosa. However, inadequate bowel preparation (IBP) had been unexpectedly reported in up to 30% of patients undergoing colonoscopy. Many factors may influence the quality of bowel preparation, which can be broadly categorized as patient-related or procedure-related. It has been shown that split-dose regimen or some modified educational strategies can improve the quality of bowel preparation. For the patients with possible IBP before the performing of colonoscopy, it may be better to repeat bowel preparation with modified or enhanced strategies in case of failed intubation, missed lesions or unnecessarily increased cost. Thus, it is important to set up a model to predict the quality of bowel preparation individually.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients aged 18-90 years old who undergoing colonoscopy
排除标准
- •failed colonoscopy because of technical chanllenge or poor tolerance of patients
- •history of colorectal surgery
- •prior finding of severe colonic stricture or obstructing tumor
- •dysphagia
- •compromised swallowing reflex or mental status
- •significant gastroparesis or gastric outlet obstruction or ileum
- •known or suspected bowel obstruction or perforation
- •pregnancy
- •unable to give informed consent
结局指标
主要结局
Adequate bowel preparation quality at the time of colonoscopy defined by Ottawa score<6
时间窗: up to 4 months
Ottawa score：A)cleanliness of each part of the colon: 0=excellent 1=good 2=fair 3=poor 4=inadequate B)fluid in whole colon: small=0 moderate=1 large=2 The bowel preparation was considered inadequate if (1) inadequate visualization on colonoscopy defined by Ottawa score≥6; (2) the colonoscopy was cancelled because of poor bowel preparation or personal reasons.
次要结局
- Polyp detection rate(up to 4 months)
研究者
Yanglin Pan
Associated professor
Air Force Military Medical University, China