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临床试验/CTRI/2018/07/015126
CTRI/2018/07/015126尚未招募不适用

Pre and post study to assess the combined effect of Anutaila nasya,mahoushada anjana and jeevanthyaadi ghrita tarpana in dry eye syndrome(shushkashipaka)

deepthi k nair1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2018年8月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
reduction in symptoms

研究概览

简要总结

Dry Eye Disease is recognized as a growing health problem and one of themost frequent reasons for seeking eye care. In India, the rural as well asurban population suffers from dry eye disease. The incidence is quite higher amongstoutdoor workers and people from rural areas with poor socioeconomic status andalso due to the modern life style and global warming, the population sufferingfrom dry eye disease are increasing day by day.

Hence there is a need to finda safe and effective medication.The modern definition of dry eye disease is based on the concept of thethree layers of the tear film. Secondary factors such as pathological changesto the eyelids, cornea, or conjunctiva, can themselves disturb the normalfunction of the tear film.

Shushkakshipaka is one among the SarvagathaNetra Rogas characterized by*; Gharsha*(Irritation), Kunita (Photophobia), Avila Darshana (Blurred vision), Toda (Pricking type of pain), Daha (Burning sensation) and Raktharaji (Congestion). So the symptoms of Dry eye syndrome can be co-related with the symptoms Shushkakshipaka mentioned in ayurvedicclassics

Anutaila nasya, Mahoushada Anjana, Jeevanthyadi ghrita tarpana are mentionedas a treatment of Shushkakshipaka both in Ashtanga gridaya and Susruta samhitauttara sthana. The previous researcheshave evaluated the efficacy of single combination. Here my present study aim isto evaluate the combined effect of the Anu taila nasya, Mahoushada Anjana,Jeevanthyadi ghrita tarpana in Dry eye syndrome (Shushkakshipaka).

This is a pre and post design where 40patients of both sex, in an age limit of 10-70 yrs, fulfilling the diagnosticcriteria   will be registered for thepresent study according to inclusion criteria. The patients will be selected from OPD & IPD of Department of Shalakyatantra,Amrita school of Ayurveda Hospital, Vallikkavu, Kollam. Subjective andObjective parameters before and after treatment will be recorded meticulouslyand analysed by using appropriate statistical methods, the Paired t test andWilcoxon signed rank test with Bonferronni correction and  final conclusion will be drawn.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
10.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Satisfying the diagnostic criteria Tear film Break up time less than 10sec Schirmers test positive less than 10mm Patients fit for Nasya Anjana Tarpana karmas.

排除标准

  • Patient suffering from any systemic diseases like SLE Rheumatic arthritis Sjogrens Syndrome and receiving medication Sever case of Dry Eye Syndrome with complications like corneal ulcer Uveitis Glaucoma Patients having poorly controlled hypertension and diabetic mellitus Patients who are using drug like antihistamines decongestants, hormonal therapy antidepressants dermatologic medication anti psychotic and chemotherapy medications Women who are pregnant or lactating Congenital anomalies of eye Patient contraindicated for Nasya Anjana and Tarpana karma.

结局指标

主要结局

reduction in symptoms

时间窗: within one month

次要结局

  • na(na)

研究者

发起方
deepthi k nair
申办方类型
Other [na]

研究点 (1)

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